3α-Fluoroandrost-5-ene-17β,19-diol diacetate

Base Information

Chemical Name:3α-Fluoroandrost-5-ene-17β,19-diol diacetate
CAS No.:28344-48-1
Molecular Formula:C23H33FO4
Molecular Weight:392.5041232
Hs Code.:
Mol file:28344-48-1.mol

Synonyms:Acetic acid (3R,8R,9S,10S,13S,14S,17S)-17-acetoxy-3-fluoro-13-methyl-1,2,3,4,7,8,9,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-10-ylmethyl ester;

Suppliers and Price of 3α-Fluoroandrost-5-ene-17β,19-diol diacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3α-Fluoroandrost-5-ene-17β,19-diol diacetate

Chemical Property:

Melting Point:115 °C
PSA：52.60000
LogP:4.76220

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3α-Fluoroandrost-5-ene-17β,19-diol diacetate

There total 3 articles about 3α-Fluoroandrost-5-ene-17β,19-diol diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-19-7,77671-22-8
acetic acid

: C₂₁H₃₀BrFO₃

: 28344-48-1
3α-Fluor-17β,19-diacetoxy-5-androsten

Guidance literature:: With zinc; at 100 ℃;

Reference yield:

: 28344-47-0
3α-Fluor-17β-acetoxy-19-hydroxy-5-androsten

: 28344-48-1
3α-Fluor-17β,19-diacetoxy-5-androsten

Guidance literature:: (acetylation);

Reference yield:

: 28344-39-0
Acetic acid (3R,5S,6R,8S,9S,10R,13S,14S,17S)-3-fluoro-10,13-dimethyl-hexadecahydro-20-oxa-cyclopropa[5,6]cyclopenta[a]phenanthren-17-yl ester

: 28344-48-1
3α-Fluor-17β,19-diacetoxy-5-androsten

Guidance literature:: Multi-step reaction with 2 steps

1: (i) aq. HBr, benzene, (ii) Pb(OAc)4, CaCO₃, cyclohexane, (iii) Zn, aq. AcOH

2: (acetylation)