rac 8α-[Δ-5(10)]-Norgestrel

Base Information

Chemical Name:rac 8α-[Δ-5(10)]-Norgestrel
CAS No.:5541-87-7
Molecular Formula:C21H28O2
Molecular Weight:312.45
Hs Code.:

Synonyms:rac 8α-[Δ-5(10)]-Norgestrel

Suppliers and Price of rac 8α-[Δ-5(10)]-Norgestrel

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac8α-[Δ-5(10)]-Norgestrel
1mg
$ 275.00

Total 4 raw suppliers

Chemical Property of rac 8α-[Δ-5(10)]-Norgestrel

Chemical Property:

PSA：37.30000
LogP:4.02670

Purity/Quality:

97% ^*data from raw suppliers

rac8α-[Δ-5(10)]-Norgestrel ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses An impurity of the ovulation inhibiting steroid Norgestrel (N689500).

Technology Process of rac 8α-[Δ-5(10)]-Norgestrel

There total 9 articles about rac 8α-[Δ-5(10)]-Norgestrel which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 848-07-7
(+/-)-13-ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,8,14-pentaen-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd-C / methanol

2: NaBH₄ / ethanol

3: Li, liq. NH₃, EtOH / tetrahydrofuran

4: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; hydrogen; lithium; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00321a016

Reference yield:

: (+/-)-13-ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,8-tetraen-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd-C / methanol; tetrahydrofuran

2: NaBH₄ / ethanol

3: Li, liq. NH₃, EtOH / tetrahydrofuran

4: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; hydrogen; lithium; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00321a016

Reference yield:

: 848-04-4,968-74-1,2445-28-5,5914-87-4,6161-35-9,7373-93-5,7434-80-2,17092-07-8,19301-69-0,31266-48-5,107598-32-3
(+/-)-13-ethyl-3-methoxy-8α-gona-1,3,5(10)-trien-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄ / ethanol

2: Li, liq. NH₃, EtOH / tetrahydrofuran

3: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; lithium; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00321a016