(S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID

Base Information

Chemical Name:(S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID
CAS No.:18652-97-6
Molecular Formula:C12H17NO5
Molecular Weight:255.27
Hs Code.:2922509090
Mol file:18652-97-6.mol

Synonyms:(S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID;L-3,4,5-TRIMETHOXYPHENYLALANINE;3,4,5-TriMethoxy-L-phenylalanine;(2S)-2-AMINO-3-(3,4,5-TRIMETHOXYPHENYL)PROPANOIC ACID

Suppliers and Price of (S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2S)-2-AMINO-3-(3,4,5-TRIMETHOXYPHENYL)PROPANOIC ACID 95.00%
5MG
$ 504.65

Activate Scientific
3,4,5-Trimethoxy-L-phenylalanine 95% ee
5 g
$ 832.00

Activate Scientific
3,4,5-Trimethoxy-L-phenylalanine 95% ee
1 g
$ 274.00

Total 9 raw suppliers

Chemical Property of (S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID

Chemical Property:

PSA：91.01000
LogP:1.36710

Purity/Quality:

98%min ^*data from raw suppliers

(2S)-2-AMINO-3-(3,4,5-TRIMETHOXYPHENYL)PROPANOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID

There total 1 articles about (S)-2-AMINO-3-(3,4,5-TRIMETHOXY-PHENYL)-PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (Z)-2-[(S)-2-Amino-3-(3,4,5-trimethoxy-phenyl)-propionylamino]-3-(3,4,5-trimethoxy-phenyl)-N-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-acrylamide

: 18652-97-6
3,4,5-trimethoxy-L-phenylalanine

Guidance literature:: With hydrogenchloride;
DOI:10.1021/ja00226a035

Reference yield: 80.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 18652-97-6
3,4,5-trimethoxy-L-phenylalanine

: 477254-82-3
(S)-2-((tert-butoxycarbonyl)amino)-3-(3,4,5-trimethoxyphenyl)propanoic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; at 20 ℃; for 4h;
DOI:10.1021/jm049660v

Reference yield:

: 18652-97-6
3,4,5-trimethoxy-L-phenylalanine

: 849752-69-8
[(S)-1-[(S)-1-(2-hydroxy-4-methoxybenzylcarbamoyl)-2-methylpropylcarbamoyl]-2-(3,4,5-trimethoxyphenyl)ethyl]carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / aq. NaOH / dioxane / 4 h / 20 °C

2: 65 percent / DIEA; TPTU / dimethylformamide / 3 h / 20 °C

With sodium hydroxide; O-(1,2-dihydro-2-oxo-1-pyridyl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1021/jm049660v