[2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Base Information

Chemical Name:[2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
CAS No.:211242-48-7
Molecular Formula:C14H18FNO3
Molecular Weight:267.3
Hs Code.:2924299090
Mol file:211242-48-7.mol

Synonyms:[2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl (1-(4-fluorophenyl)-1-oxopropan-2-yl)carbamate

Suppliers and Price of [2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
tert-Butyl N-[1-(4-fluorophenyl)-1-oxopropan-2-yl]carbamate 96%
1 g
$ 1595.00

SynQuest Laboratories
tert-Butyl N-[1-(4-fluorophenyl)-1-oxopropan-2-yl]carbamate 96%
250 mg
$ 591.00

American Custom Chemicals Corporation
(2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL)-CARBAMIC ACID TERT-BUTYL ESTER 96.00%
5MG
$ 502.62

Total 3 raw suppliers

Chemical Property of [2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

Chemical Property:

PSA：58.89000
LogP:3.12600

Purity/Quality:

≥95% ^*data from raw suppliers

tert-Butyl N-[1-(4-fluorophenyl)-1-oxopropan-2-yl]carbamate 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of [2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER

There total 7 articles about [2-(4-FLUORO-PHENYL)-1-METHYL-2-OXO-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 322-30-5
2-amino-1-(4-fluorophenyl)-1-propanone hydrochloride

: 211242-48-7
2-N-tert-butoxycarbonylamino-1-(4-fluorophenyl)-1-propanone

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide;
DOI:10.1002/1099-1344(200012)43:14<1345::AID-JLCR424>3.0.CO;2-N

Reference yield: 76.0%

: 352-13-6
4-flourophenylmagnesium bromide

: 342603-65-0
(+/-)-tert-butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate

: 211242-48-7
2-N-tert-butoxycarbonylamino-1-(4-fluorophenyl)-1-propanone

Guidance literature:: In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1021/acs.jmedchem.7b01210

Reference yield: 65.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 342603-65-0
(+/-)-tert-butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate

: 211242-48-7
2-N-tert-butoxycarbonylamino-1-(4-fluorophenyl)-1-propanone

Guidance literature:: 1-Bromo-4-fluorobenzene; With magnesium; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

(+/-)-tert-butyl (1-(methoxy(methyl)amino)-1-oxopropan-2-yl)carbamate; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;