N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl)

Base Information

• Chemical Name: N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl)
• CAS No.: 900641-74-9
• Molecular Formula: C₈H₉BrN₂O
• Molecular Weight: 229.076
• Hs Code.: 2924299090
• Mol file: 900641-74-9.mol

Synonyms:N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl)

Chemical Property of N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl)

Chemical Property:

• PSA: 58.61000
• LogP: 2.69610

Purity/Quality:

98% ^*data from raw suppliers

2-AMINO-N-(2-BROMOPHENYL)ACETAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl)

There total 2 articles about N~1~-(2-bromophenyl)glycinamide(SALTDATA: HCl) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

[(2-bromophenylcarbamoyl)methyl]carbamic acid tert-butyl ester → C8H9BrN2O (900641-74-9)

Guidance literature:

With trifluoroacetic acid; In tetrahydrofuran; dichloromethane; at 20 ℃; Inert atmosphere;

Reference yield:

2-bromoaniline (615-36-1) → C8H9BrN2O (900641-74-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / ethyl acetate / 16 h / 20 °C / Inert atmosphere

2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

With pyridine; trifluoroacetic acid; In dichloromethane; ethyl acetate;

DOI:10.1002/ejoc.202200152

upstream raw materials:

2-bromoaniline

Refernces

• 1、 -. "SERINE RACEMASE INHIBITOR". Paragraph 0224. . Retrieved 2014/12/12.