4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine

Base Information

Chemical Name:4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine
CAS No.:35808-69-6
Molecular Formula:C8H8ClN3
Molecular Weight:181.62222
Hs Code.:
Mol file:35808-69-6.mol

Synonyms:4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine

Suppliers and Price of 4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
4-Chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine 95+%
1g
$ 880.00

Chemenu
4-chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine 95%
1g
$ 830.00

Alichem
4-Chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine
1g
$ 721.14

Total 2 raw suppliers

Chemical Property of 4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine

Chemical Property:

PSA：30.71000
LogP:1.93010

Purity/Quality:

≥99% ^*data from raw suppliers

4-Chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine

There total 6 articles about 4-Chloro-6,7-diMethyl-7H-pyrrolo[2,3-d]pyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35808-68-5
4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

: 74-88-4
methyl iodide

: 35808-69-6
4-chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.25h;

methyl iodide; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 1h; Concentration;

Reference yield:

: 3680-69-1
4-chloro-1H-pyrrolo[2,3-d]pyrimidine

: 35808-69-6
4-chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C

1.2: 1 h / 0 - 20 °C

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

2.2: 1 h / -78 °C

3.1: trifluoroacetic acid / dichloromethane / 16 h / 0 - 20 °C

4.1: boron trifluoride diethyl etherate / tetrahydrofuran / 24 h / 20 °C

5.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C

5.2: 1 h / 0 - 20 °C

With boron trifluoride diethyl etherate; sodium hydride; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 941685-26-3
4-chloro-7-((2-(trimethylsilyl)ethoxy)methyl)-7H-pyrrolo[2,3-d]pyrimidine

: 35808-69-6
4-chloro-6,7-dimethyl-7H-pyrrolo[2,3-d]pyrimidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

1.2: 1 h / -78 °C

2.1: trifluoroacetic acid / dichloromethane / 16 h / 0 - 20 °C

3.1: boron trifluoride diethyl etherate / tetrahydrofuran / 24 h / 20 °C

4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.25 h / 0 °C

4.2: 1 h / 0 - 20 °C

With boron trifluoride diethyl etherate; sodium hydride; trifluoroacetic acid; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; mineral oil;