1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane

Base Information

Chemical Name:1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane
CAS No.:136705-63-0
Molecular Formula:C22H44P2
Molecular Weight:370.53
Hs Code.:
European Community (EC) Number:814-336-8
DSSTox Substance ID:DTXSID201144734
Nikkaji Number:J1.127.353J
Mol file:136705-63-0.mol

Synonyms:136705-63-0;1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane;1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane;1,2-Bis[(2R,5R)-2,5-diisopropyl-1-phospholanyl]ethane;Phospholane, 1,1'-(1,2-ethanediyl)bis[2,5-bis(1-methylethyl)-, (2R,2'R,5R,5'R)-;(2R,5R)-1-[2-[(2R,5R)-2,5-di(propan-2-yl)phospholan-1-yl]ethyl]-2,5-di(propan-2-yl)phospholane;MFCD08705243;(R,R)-Isopropyl-BPE;SCHEMBL21896516;DTXSID201144734;CS-0106017;D83769;J-006888;1,2-Bis((2R,5R)-2,5-di-i-propylphospholano)ethane;1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane, kanata purity;1,2-Bis[(2S,5S)-2,5-diisopropylphospholano]ethane, kanata purity;(2R,2'R,5R,5'R)-1,1'-(1,2-Ethanediyl)bis[2,5-bis(1-methylethyl)phospholane

Suppliers and Price of 1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Strem Chemicals
1,2-Bis((2R,5R)-2,5-di-i-propylphospholano)ethane, 96%
100mg
$ 78.00

Strem Chemicals
1,2-Bis((2R,5R)-2,5-di-i-propylphospholano)ethane, 96%
500mg
$ 308.00

Sigma-Aldrich
1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane kanata purity
2g
$ 1250.00

Sigma-Aldrich
1,2-Bis[(2R,5R)-2,5-diisopropylphospholano]ethane kanata purity
500mg
$ 296.00

Arctom
1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane 98%
250mg
$ 147.00

Arctom
1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane 98%
100mg
$ 67.00

Arctom
1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane 98%
500mg
$ 265.00

American Custom Chemicals Corporation
1,2-BIS[(2R,5R)-2,5-DIISOPROPYLPHOSPHOLANO]ETHANE 95.00%
2G
$ 1911.53

American Custom Chemicals Corporation
1,2-BIS[(2R,5R)-2,5-DIISOPROPYLPHOSPHOLANO]ETHANE 95.00%
500MG
$ 924.72

American Custom Chemicals Corporation
1,2-BIS[(2R,5R)-2,5-DIISOPROPYLPHOSPHOLANO]ETHANE 95.00%
100MG
$ 640.46

Total 8 raw suppliers

Chemical Property of 1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane

Chemical Property:

Melting Point:67-72℃
Boiling Point:434.5±15.0 °C(Predicted)
PSA：27.18000
LogP:7.63620
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Sensitive.:Air Sensitive
XLogP3:6.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:0
Rotatable Bond Count:7
Exact Mass:370.29182540
Heavy Atom Count:24
Complexity:306

Purity/Quality:

98% ^*data from raw suppliers

1,2-Bis((2R,5R)-2,5-di-i-propylphospholano)ethane, 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1CCC(P1CCP2C(CCC2C(C)C)C(C)C)C(C)C
Isomeric SMILES:CC(C)[C@H]1CC[C@@H](P1CCP2[C@H](CC[C@@H]2C(C)C)C(C)C)C(C)C

Technology Process of 1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane

There total 3 articles about 1,2-Bis((2R,5R)-2,5-diisopropylphospholan-1-yl)ethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 129705-30-2
(3S,6S)-3,6-dihydroxy-2,7-dimethyloctane

: 136705-63-0
1,2-bis((2R,5R)-2,5-diisopropylphospholano)ethane

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) SOCl₂, 2.) RuCl₃*3H₂O, NaIO₄ / 1.) CCl₄, reflux, 1.5 h, 2.) CCl₄, CH₃CN, H₂O, 25 deg C, 1 h

2: 1.) n-BuLi, 3.) n-BuLi

With ruthenium trichloride; sodium periodate; n-butyllithium; thionyl chloride;