3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr)

Base Information

• Chemical Name: 3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr)
• CAS No.: 41886-04-8
• Molecular Formula: C₇H₁₄BrN
• Molecular Weight: 192.099
• Hs Code.: 2933399090
• Mol file: 41886-04-8.mol

Synonyms:3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr);3-(Bromomethyl)-1-methylpiperidine hydrobromide

Chemical Property of 3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr)

Chemical Property:

• PSA: 3.24000
• LogP: 1.66100

Purity/Quality:

98%min ^*data from raw suppliers

3-(bromomethyl)-1-methylpiperidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr)

There total 2 articles about 3-(bromomethyl)-1-methylpiperidine(SALTDATA: HBr) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-methyl-3-hydroxymethylpiperidine (7583-53-1,230294-57-2) → 3-bromomethyl-1-methylpiperidine (41886-04-8)

Guidance literature:

With pyridine; dibromotriphenylphosphorane; In acetonitrile; at 0 - 25 ℃; for 94h;

Reference yield: 100.0%

1-methyl-3-hydroxymethylpiperidine (7583-53-1,230294-57-2) + dibromotriphenylphosphorane (1034-39-5) → 3-bromomethyl-1-methylpiperidine (41886-04-8)

Guidance literature:

With pyridine; In methanol; dichloromethane; acetonitrile;

Reference yield:

3-bromomethyl-1-methylpiperidine (41886-04-8) + (S)-1-(3-hydroxy-4-methoxyphenyl)-3-(1-phenyl-ethyl)-urea (1362624-32-5) → C23H31N3O3 (1362625-77-1)

Guidance literature:

With 18-crown-6 ether; potassium carbonate; In N,N-dimethyl-formamide; for 12h; Inert atmosphere;

DOI:10.1021/ml300005w

upstream raw materials:

1-methyl-3-hydroxymethylpiperidine

dibromotriphenylphosphorane

Downstream raw materials:

C₂₃H₃₁N₃O₃

Refernces

• 1、 -. "Novel pyrazolopyrimidines as cyclin dependent kinase inhibitors". . . Retrieved 2008/06/13.