Sergliflozin A

Base Information

Chemical Name:Sergliflozin A
CAS No.:360775-96-8
Molecular Formula:C20H24O7
Molecular Weight:376.406
Hs Code.:
UNII:AR34521QFL
ChEMBL ID:CHEMBL270766
Nikkaji Number:J3.551.075C
Pharos Ligand ID:HJ4Q77ZNLBG7
Mol file:360775-96-8.mol

Synonyms:sergliflozin

Suppliers and Price of Sergliflozin A

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of Sergliflozin A

Chemical Property:

PSA：134.91000
LogP:1.16700
XLogP3:1.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:376.15220310
Heavy Atom Count:27
Complexity:440

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)CC2=CC=CC=C2OC3C(C(C(C(O3)CO)O)O)O
Isomeric SMILES:COC1=CC=C(C=C1)CC2=CC=CC=C2O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O

Technology Process of Sergliflozin A

There total 17 articles about Sergliflozin A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 360775-87-7
2-[(4-methoxyphenyl)methyl]phenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside

: 360775-96-8
Sergliflozin A

Guidance literature:: With sodium methylate; In methanol; at 25 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2016.03.065

Reference yield: 82.0%

: 7234-29-9
2-iodophenyl β-D-glucopyranoside

: 824-94-2
p-methoxybenzyl chloride

: 360775-96-8
Sergliflozin A

Guidance literature:: p-methoxybenzyl chloride; With indium; chloro-trimethyl-silane; ethylene dibromide; lithium chloride; In tetrahydrofuran; at 40 ℃; for 15h; Inert atmosphere;

With TurboGrignard; In tetrahydrofuran; at -60 - -50 ℃; Inert atmosphere;

2-iodophenyl β-D-glucopyranoside; With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; In tetrahydrofuran; water; at 40 ℃; for 3.5h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/anie.200805588