2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)

Base Information

• Chemical Name: 2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)
• CAS No.: 210417-14-4
• Molecular Formula: C8H12N4O
• Molecular Weight: 180.20708
• Hs Code.: 2933990090
• Mol file: 210417-14-4.mol

Synonyms:2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)

Chemical Property of 2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)

Chemical Property:

• PSA: 87.66000
• LogP: 0.59680

Purity/Quality:

97% ^*data from raw suppliers

3-Oxo-1,3,4,5,6,7-Hexahydro-2h-Indazole-2-Carboximidamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI)

There total 1 articles about 2H-Indazole-2-carboximidamide,1,3,4,5,6,7-hexahydro-3-oxo-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.6%

aminoguanidine bicarbonate (2582-30-1) + ethyl 2-oxocyclohexane carboxylate (1655-07-8) → 2-amidino-1,2,4,5,6,7-hexahydro-3H-indazol-3-one (210417-14-4)

Guidance literature:

With ammonium acetate; In ethanol; Heating;

DOI:10.1016/S0223-5234(98)80002-0

Reference yield: 93.7%

diethyl 2-ethoxymethylenemalonate (87-13-8) + 2-amidino-1,2,4,5,6,7-hexahydro-3H-indazol-3-one (210417-14-4) → 6-Oxo-2-(3-oxo-1,3,4,5,6,7-hexahydro-indazol-2-yl)-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester (210417-26-8)

Guidance literature:

With potassium carbonate; In ethanol; Heating;

DOI:10.1016/S0223-5234(98)80002-0

Reference yield: 67.0%

diethyl 2-phenylmalonate (83-13-6) + 2-amidino-1,2,4,5,6,7-hexahydro-3H-indazol-3-one (210417-14-4) → 2-(4-Hydroxy-6-oxo-5-phenyl-1,6-dihydro-pyrimidin-2-yl)-1,2,4,5,6,7-hexahydro-indazol-3-one

Guidance literature:

With sodium methylate; In methanol; Heating;

DOI:10.1016/S0223-5234(98)80002-0

upstream raw materials:

aminoguanidine bicarbonate

ethyl 2-oxocyclohexane carboxylate

Downstream raw materials:

6-Oxo-2-(3-oxo-1,3,4,5,6,7-hexahydro-indazol-2-yl)-1,6-dihydro-pyrimidine-5-carboxylic acid ethyl ester