6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine

Base Information

Chemical Name:6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine
CAS No.:1364663-35-3
Molecular Formula:C14H22N4O4
Molecular Weight:310.353
Hs Code.:29335990
Mol file:1364663-35-3.mol

Synonyms:6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine;(6-AMinopyriMidin-4-yl)-N-(tert-butoxycarbonyl)carbaMic acid tert-butyl ester;di-tert-butyl (6-aMinopyriMidin-4-yl)carbaMate;tert-Butyl (6-aMinopyriMidin-4-yl)(tert-butyl)carbaMate;tert-Butyl N-(6-aminopyrimidin-4-yl)-N-tert-butoxycarbonyl-carbamate

Suppliers and Price of 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
Di-tert-butyl (6-aminopyrimidin-4-yl)carbamate
1 g
$ 436.00

Chemenu
tert-butyl(6-aminopyrimidin-4-yl)(tert-butyl)carbamate 95%
1g
$ 281.00

Chemenu
tert-butyl(6-aminopyrimidin-4-yl)(tert-butyl)carbamate 95%
5g
$ 1122.00

Apolloscientific
Di-tert-butyl(6-aminopyrimidin-4-yl)carbamate
1g
$ 395.00

Alichem
Di-tert-butyl(6-aminopyrimidin-4-yl)carbamate
5g
$ 930.62

Total 11 raw suppliers

Chemical Property of 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine

Chemical Property:

Boiling Point:436.2±55.0 °C(Predicted)
PKA:4.23±0.10(Predicted)
PSA：107.64000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:3.31660

Purity/Quality:

97% ^*data from raw suppliers

Di-tert-butyl (6-aminopyrimidin-4-yl)carbamate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine

There total 3 articles about 6-[bis(tert-butoxycarbonyl)aMino]-4-aMinopyriMidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1365992-75-1
(6-azidopyrimidin-4-yl)-bis-carbamic acid tert-butyl ester

: 1364663-35-3
6-amino-(pyrimidin-4-yl)-bis-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In industrial methylated spirits; ethyl acetate; at 20 ℃; for 18h;

Reference yield:

: 354112-08-6
tert-butyl N-tert-butoxycarbonyl-N-(6-chloropyrimidin-4-yl)carbamate

: 1364663-35-3
6-amino-(pyrimidin-4-yl)-bis-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / 4 h / 70 °C

2: hydrogen / 5%-palladium/activated carbon / ethyl acetate; industrial methylated spirits / 18 h / 20 °C

With sodium azide; hydrogen; 5%-palladium/activated carbon; In industrial methylated spirits; ethyl acetate;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 1364663-35-3
6-amino-(pyrimidin-4-yl)-bis-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: dmap / tetrahydrofuran / 6 h / 20 °C

2: sodium azide / N,N-dimethyl-formamide / 4 h / 70 °C

3: palladium on activated charcoal / ethyl acetate; industrial methylated spirits / 18 h / 20 °C / Inert atmosphere

With dmap; sodium azide; palladium on activated charcoal; In tetrahydrofuran; industrial methylated spirits; ethyl acetate; N,N-dimethyl-formamide;