cis-1-Amino-indan-2-carboxylic acid

Base Information

Chemical Name:cis-1-Amino-indan-2-carboxylic acid
CAS No.:135053-20-2
Molecular Formula:C₁₀H₁₁NO₂
Molecular Weight:177.203
Hs Code.:2922498590
European Community (EC) Number:801-937-5
Nikkaji Number:J386.424C
Mol file:135053-20-2.mol

Synonyms:cis-1-Amino-indan-2-carboxylic acid;135053-20-2;(1R,2R)-1-AMINO-2,3-DIHYDRO-1H-INDENE-2-CARBOXYLIC ACID;758675-47-7;SCHEMBL15036610;MFCD09260354;AKOS006283235;CS-0287452;EN300-1168695;EN300-1716874;rac-(1R,2R)-1-amino-2,3-dihydro-1H-indene-2-carboxylic acid

Suppliers and Price of cis-1-Amino-indan-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
CIS-1-AMINO-INDAN-2-CARBOXYLIC ACID 95.00%
5MG
$ 496.49

Total 6 raw suppliers

Chemical Property of cis-1-Amino-indan-2-carboxylic acid

Chemical Property:

Vapor Pressure:6.34E-06mmHg at 25°C
Boiling Point:363.6°C at 760 mmHg
Flash Point:173.7°C
PSA：63.32000
Density:1.28g/cm³
LogP:1.64360
XLogP3:-1.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:217

Purity/Quality:

98%Min ^*data from raw suppliers

CIS-1-AMINO-INDAN-2-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(C(C2=CC=CC=C21)N)C(=O)O
Isomeric SMILES:C1[C@H]([C@H](C2=CC=CC=C21)N)C(=O)O

Technology Process of cis-1-Amino-indan-2-carboxylic acid

There total 7 articles about cis-1-Amino-indan-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: (±)-3,4-benzo-cis-6-azabicyclo[3.2.0]heptane-7-one

: 874292-64-5
(1S,5S)-3,4-benzo-6-azabicyclo[3.2.0]heptan-7-one

: 135053-20-2,887127-22-2
(1R,2R)-1-amino-2,3-dihydro-1H-indene-2-carboxylic acid

Guidance literature:: With water; In di-isopropyl ether; at 60 ℃; Inert atmosphere; Resolution of racemate; Enzymatic reaction;
DOI:10.1021/ml300407y

Reference yield:

: (±)-3,4-benzo-cis-6-azabicyclo[3.2.0]heptane-7-one

: 874292-63-4
(2aR,7bR)-2a,3-dihydro-1H-indeno[1,2-b]azet-2(7bH)-one

: 135053-20-2,887127-22-2
(1S,2S)-1-amino-2,3-dihydro-1H-indene-2-carboxylic acid

Guidance literature:: With water; In di-isopropyl ether; at 60 ℃; Inert atmosphere; Resolution of racemate; Enzymatic reaction;
DOI:10.1021/ml300407y

Reference yield:

: 95-13-6
1-indene

: 874292-64-5
(1S,5S)-3,4-benzo-6-azabicyclo[3.2.0]heptan-7-one

: 135053-20-2,887127-22-2
(1R,2R)-1-amino-2,3-dihydro-1H-indene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: diethyl ether / 3 h / 20 °C / Inert atmosphere

2: water / di-isopropyl ether / 60 °C / Inert atmosphere; Resolution of racemate; Enzymatic reaction

With water; In diethyl ether; di-isopropyl ether; 1: |Diels-Alder Cycloaddition;
DOI:10.1021/ml300407y