2-(Aminomethyl)thiazole-4-carboxamide

Base Information

Chemical Name:2-(Aminomethyl)thiazole-4-carboxamide
CAS No.:203793-16-2
Molecular Formula:C5H7N3OS
Molecular Weight:157.19
Hs Code.:
European Community (EC) Number:857-264-2
Mol file:203793-16-2.mol

Synonyms:2-(aminomethyl)thiazole-4-carboxamide;203793-16-2;2-(aminomethyl)-1,3-thiazole-4-carboxamide;SCHEMBL2642449;AKOS013567556;4-Thiazolecarboxamide, 2-(aminomethyl)-;DB-272909;EN300-303598;G56423

Suppliers and Price of 2-(Aminomethyl)thiazole-4-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 2-(Aminomethyl)thiazole-4-carboxamide

Chemical Property:

PSA：111.23000
LogP:1.28520
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:157.03098303
Heavy Atom Count:10
Complexity:141

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(N=C(S1)CN)C(=O)N

Technology Process of 2-(Aminomethyl)thiazole-4-carboxamide

There total 2 articles about 2-(Aminomethyl)thiazole-4-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 182120-82-7
2-(tert-butoxycarbonylaminomethyl)-1,3-thiazole-4-carboxamide

: 203793-16-2
2-(aminomethyl)thiazole-4-carboxamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h;
DOI:10.1016/j.cell.2018.04.037

Reference yield:

: 96929-05-4
ethyl 2-[N-(tert-butoxycarbonyl)aminomethyl]thiazole-4-carboxylate

: 203793-16-2
2-(aminomethyl)thiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / methanol / 16 h / 45 °C

2: trifluoroacetic acid / dichloromethane / 1.5 h / 20 °C

With ammonium hydroxide; trifluoroacetic acid; In methanol; dichloromethane;
DOI:10.1016/j.cell.2018.04.037