Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate

Base Information

Chemical Name:Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate
CAS No.:20949-28-4
Molecular Formula:C14H17NO2
Molecular Weight:231.294
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80701366
Wikidata:Q82632983
Mol file:20949-28-4.mol

Synonyms:ETHYL 2-(1H-INDOL-2-YL)-2-METHYLPROPANOATE;20949-28-4;SCHEMBL1466155;DTXSID80701366;RLZKIOZEXCKNCF-UHFFFAOYSA-N

Suppliers and Price of Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ETHYL-2-(1H-INDOL-2-YL)-2-METHYLPROPANOATE 95.00%
5MG
$ 497.98

Total 3 raw suppliers

Chemical Property of Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate

Chemical Property:

Melting Point:120-122 °C
Boiling Point:363.9±17.0 °C(Predicted)
PKA:16.81±0.30(Predicted)
PSA：42.09000
Density:1.127±0.06 g/cm3(Predicted)
LogP:3.00860
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:231.125928785
Heavy Atom Count:17
Complexity:288

Purity/Quality:

99% ^*data from raw suppliers

ETHYL-2-(1H-INDOL-2-YL)-2-METHYLPROPANOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)(C)C1=CC2=CC=CC=C2N1

Technology Process of Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate

There total 4 articles about Ethyl 2-(1H-indol-2-YL)-2-methylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 172226-79-8
tert-butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

: 20949-28-4
ethyl 2-(1H-indol-2-yl)-2-methylpropanoate

Guidance literature:: With trifluoroacetic acid; In dichloromethane; Ambient temperature;
DOI:10.1039/a800278i

Reference yield: 24.0%

: 120-72-9
indole

: 600-00-0
ethyl 2-bromoisobutyrate

: 20949-28-4
ethyl 2-(1H-indol-2-yl)-2-methylpropanoate

Guidance literature:: With 2,4,6-trimethyl-pyridine; copper(l) iodide; tris[(2-pyridylmethyl)amine]; In 1,4-dioxane; at 150 ℃; for 48h;
DOI:10.1039/c6sc05622a

Reference yield:

: 597-04-6
ethyl 2,2-dimethyl-3-oxobutanoate

: 20949-28-4
ethyl 2-(1H-indol-2-yl)-2-methylpropanoate

Guidance literature:: With chloroform; bromine; Behandeln des Reaktionsprodukts mit Anilin und anschliessenden Erhitzen auf 140grad bis 150grad;