tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

Base Information

Chemical Name:tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate
CAS No.:172226-79-8
Molecular Formula:C₁₉H₂₅NO₄
Molecular Weight:331.412
Hs Code.:
DSSTox Substance ID:DTXSID50701737
Nikkaji Number:J946.918D
Wikidata:Q82633505
Mol file:172226-79-8.mol

Synonyms:172226-79-8;SCHEMBL1465436;DTXSID50701737;tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate;tert-Butyl 2-(1-ethoxy-2-methyl-1-oxopropan-2-yl)-1H-indole-1-carboxylate;2-(1,1-Dimethyl-2-oxo-2-ethoxyethyl)-1H-indole-1-carboxylic acid tert-butyl ester

Suppliers and Price of tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TERT-BUTYL-2-(2-ETHOXY-1,1-DIMETHYL-2-OXOETHYL)-1H-INDOLE-1-CARBOXYLATE 95.00%
5MG
$ 504.68

Total 5 raw suppliers

Chemical Property of tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

Chemical Property:

PSA：57.53000
LogP:4.26520
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:331.17835828
Heavy Atom Count:24
Complexity:480

Purity/Quality:

99% ^*data from raw suppliers

TERT-BUTYL-2-(2-ETHOXY-1,1-DIMETHYL-2-OXOETHYL)-1H-INDOLE-1-CARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(C)(C)C1=CC2=CC=CC=C2N1C(=O)OC(C)(C)C

Technology Process of tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

There total 5 articles about tert-Butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 74-88-4
methyl iodide

: 172226-79-8
tert-butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

Guidance literature:: tert-butyl 2-((ethoxycarbonyl)methyl)-1H-indole-1-carboxylate; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 - -60 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 0.5h;

methyl iodide; With potassium hexamethylsilazane; more than 3 stages;

Reference yield: 94.0%

: 172226-77-6
tert-butyl 2-((ethoxycarbonyl)methyl)-1H-indole-1-carboxylate

: 74-88-4
methyl iodide

: 172226-79-8
tert-butyl 2-(2-(ethoxycarbonyl)propan-2-yl)-1H-indole-1-carboxylate

Guidance literature:: tert-butyl 2-((ethoxycarbonyl)methyl)-1H-indole-1-carboxylate; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 - -60 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 0.5h;

methyl iodide; Further stages;