(1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER

Base Information

Chemical Name:(1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER
CAS No.:165881-36-7
Molecular Formula:C₁₄H₂₄BBrO₂
Molecular Weight:315.058
Hs Code.:2933998090
Mol file:165881-36-7.mol

Synonyms:(1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER;4- Bromobutylboronate ester;4-Bromobutaneboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester;4-Bromobutylboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester, 95%

Suppliers and Price of (1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
4-Bromobutaneboronic acid(1S,2S,3R,5S)-(+)-2,3-pinanediol ester
1g
$ 648.00

Matrix Scientific
4-Bromobutaneboronic acid(1S,2S,3R,5S)-(+)-2,3-pinanediol ester
500mg
$ 522.00

Crysdot
(3aS,4S,6S,7aR)-2-(4-Bromobutyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole 97%
1g
$ 450.00

American Custom Chemicals Corporation
4-BROMOBUTANEBORONIC ACID (1S,2S,3R,5S)-(+)-2,3-PINANEDIOL ESTER 95.00%
1G
$ 408.45

Alfa Aesar
4-Bromobutylboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester, 95%
1g
$ 226.00

Alfa Aesar
4-Bromobutylboronic acid (1S,2S,3R,5S)-(+)-2,3-pinanediol ester, 95%
250mg
$ 99.80

AK Scientific
4-Bromobutaneboronicacid(1S,2S,3R,5S)-(+)-2,3-pinanediolester
500mg
$ 754.00

Total 12 raw suppliers

Chemical Property of (1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER

Chemical Property:

Vapor Pressure:0.000243mmHg at 25°C
Refractive Index:1.4960
Boiling Point:334.7°C at 760 mmHg
Flash Point:156.2°C
PSA：18.46000
Density:1.24g/cm³
LogP:3.88980

Purity/Quality:

99% ^*data from raw suppliers

4-Bromobutaneboronic acid(1S,2S,3R,5S)-(+)-2,3-pinanediol ester ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER

There total 2 articles about (1S,2S,3R,5S)-(+)-2,3-PINANEDIOL 4-BROMOBUTYLBORONATE ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 5162-44-7
1-bromo-4-butene

: 18680-27-8
pinanediol

: 165881-36-7
(+)-pinanediol-4-bromo-butane-1-boronate

Guidance literature:: 1-bromo-4-butene; With benzo[1,3,2]dioxaborole; at 110 ℃; for 18h;

pinanediol; In tetrahydrofuran; at 20 ℃; for 24h;
DOI:10.1016/S0968-0896(00)00147-4

Reference yield: 70.0%

: 5162-44-7
1-bromo-4-butene

: 18680-27-8
pinanediol

: 274-07-7
benzo[1,3,2]dioxaborole

: 165881-36-7
(+)-pinanediol-4-bromo-butane-1-boronate

Guidance literature:: 1-bromo-4-butene; benzo[1,3,2]dioxaborole; at 110 ℃; for 18h; Inert atmosphere;

pinanediol; In tetrahydrofuran; at 23 ℃; for 18h;

Reference yield:

: 165881-36-7
(+)-pinanediol-4-bromo-butane-1-boronate

: (2S,4R)-1-((R)-2-(2-naphthamido)-3-cyclohexylpropanoyl)-N-((R)-5-(4-phenyl-1H-1,2,3-triazol-1-yl)-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)pentyl)-4-(piperidin-1-yl)pyrrolidine-2-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1.1: n-butyllithium / diethyl ether; tetrahydrofuran; hexane / 0.25 h / -110 - -90 °C / Inert atmosphere

1.2: 0.25 h

1.3: 23 °C

2.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 23 °C / Inert atmosphere

2.2: 6 h / -78 - 23 °C

3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 23 °C / Inert atmosphere

4.1: sodium azide; potassium iodide / N,N-dimethyl-formamide / 18 h / 50 °C

5.1: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 3 h / 50 °C

With n-butyllithium; sodium azide; copper(ll) sulfate pentahydrate; sodium L-ascorbate; N-ethyl-N,N-diisopropylamine; potassium iodide; lithium hexamethyldisilazane; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; N,N-dimethyl-formamide; tert-butyl alcohol;