Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate

Base Information

Chemical Name:Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate
CAS No.:859521-92-9
Molecular Formula:C8H12N2O2S
Molecular Weight:200.261
Hs Code.:2934100090
European Community (EC) Number:846-185-9
Mol file:859521-92-9.mol

Synonyms:Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate;859521-92-9;Ethyl 2-(2-amino-5-methylthiazol-4-yl)acetate;SCHEMBL999513;(2-amino-5-methylthiazol-4-yl)-acetic acid ethyl ester;(2-amino-5-methyl-thiazol-4-yl)-acetic acid ethyl ester;SNCDTMINSVKXML-UHFFFAOYSA-N;MFCD08443952;AKOS005071576;AA-0716;DA-34581;CS-0243240;EN300-261323;Ethyl2-(2-amino-5-methylthiazol-4-yl)acetate;Z1269184112

Suppliers and Price of Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl2-(2-Amino-5-methyl-1,3-thiazol-4-yl)acetate
500mg
$ 175.00

SynQuest Laboratories
Ethyl (2-amino-5-methyl-1,3-thiazol-4-yl)acetate
1 g
$ 151.00

SynQuest Laboratories
Ethyl (2-amino-5-methyl-1,3-thiazol-4-yl)acetate
5 g
$ 279.00

SynQuest Laboratories
Ethyl (2-amino-5-methyl-1,3-thiazol-4-yl)acetate
10 g
$ 423.00

Matrix Scientific
Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate >95%
5g
$ 524.00

Crysdot
Ethyl2-(2-amino-5-methylthiazol-4-yl)acetate 95+%
5g
$ 363.00

Chemenu
Ethyl2-(2-amino-5-methylthiazol-4-yl)acetate 95%
5g
$ 343.00

Apolloscientific
Ethyl(2-amino-5-methyl-1,3-thiazol-4-yl)acetate
5g
$ 253.00

Apolloscientific
Ethyl(2-amino-5-methyl-1,3-thiazol-4-yl)acetate
1g
$ 137.00

Apolloscientific
Ethyl(2-amino-5-methyl-1,3-thiazol-4-yl)acetate
10g
$ 383.00

Total 3 raw suppliers

Chemical Property of Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate

Chemical Property:

Melting Point:116～118℃
Boiling Point:335.9±27.0 °C(Predicted)
PKA:4.32±0.10(Predicted)
PSA：93.45000
Density:1.251±0.06 g/cm3(Predicted)
LogP:1.72050
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:200.06194880
Heavy Atom Count:13
Complexity:189

Purity/Quality:

98%min ^*data from raw suppliers

Ethyl2-(2-Amino-5-methyl-1,3-thiazol-4-yl)acetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC1=C(SC(=N1)N)C

Technology Process of Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate

There total 2 articles about Ethyl 2-(2-amino-5-methyl-1,3-thiazol-4-yl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 36187-69-6
ethyl 4-bromo-3-oxopentanoate

: 17356-08-0
thiourea

: 859521-92-9
2-(2-amino-5-methylthiazol-4-yl)acetic acid ethyl ester

Guidance literature:: In toluene; at 110 ℃; for 3h;

Reference yield:

: 4949-44-4
ethyl propanoylacetate

: 859521-92-9
2-(2-amino-5-methylthiazol-4-yl)acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / dichloromethane / 0 - 20 °C

2: toluene / 3 h / 110 °C

With bromine; In dichloromethane; toluene;

Reference yield: 37.0%

: 300354-95-4
3-cyclopentyl-2-(4-methanesulfonyl-phenyl)propionic acid

: 859521-92-9
2-(2-amino-5-methylthiazol-4-yl)acetic acid ethyl ester

: {2-[3-cyclopentyl-2-(4-methanesulfonyl-phenyl)-propionylamino]-5-methyl-thiazol-4-yl}-acetic acid ethyl ester

Guidance literature:: 3-cyclopentyl-2-(4-methanesulfonyl-phenyl)propionic acid; With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 2h;

2-(2-amino-5-methylthiazol-4-yl)acetic acid ethyl ester; With N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 18h;