3-Bromo-6-fluoro-2-methylbenzonitrile

Base Information

Chemical Name:3-Bromo-6-fluoro-2-methylbenzonitrile
CAS No.:1255207-47-6
Molecular Formula:C8H5BrFN
Molecular Weight:214.037
Hs Code.:2926907090
Mol file:1255207-47-6.mol

Synonyms:3-BROMO-6-FLUORO-2-METHYLBENZONITRILE;1255207-47-6;3-bromo-6-fluoro-2-methyl-benzonitrile;SCHEMBL286417;UMWADFWBCUFDLC-UHFFFAOYSA-N;MFCD25542122;AS-41773;CS-0088191;FT-0702657;EN300-5421379

Suppliers and Price of 3-Bromo-6-fluoro-2-methylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Bromo-6-Fluoro-2-methylbenzonitrile
50mg
$ 155.00

Crysdot
3-Bromo-6-fluoro-2-methylbenzonitrile 95+%
1g
$ 489.00

ChemScene
3-Bromo-6-fluoro-2-methylbenzonitrile
1g
$ 939.00

ChemScene
3-Bromo-6-fluoro-2-methylbenzonitrile
250mg
$ 369.00

Chemenu
3-Bromo-6-fluoro-2-methylbenzonitrile 95%
1g
$ 462.00

Chemcia Scientific
3-Bromo-6-fluoro-2-methyl-benzonitrile ＞97%
0.5 G
$ 225.00

Alichem
3-Bromo-6-fluoro-2-methylbenzonitrile
1g
$ 1490.00

Alichem
3-Bromo-6-fluoro-2-methylbenzonitrile
500mg
$ 847.60

Alichem
3-Bromo-6-fluoro-2-methylbenzonitrile
250mg
$ 480.00

Total 5 raw suppliers

Chemical Property of 3-Bromo-6-fluoro-2-methylbenzonitrile

Chemical Property:

PSA：23.79000
LogP:2.76828
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:212.95894
Heavy Atom Count:11
Complexity:186

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-6-Fluoro-2-methylbenzonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1C#N)F)Br

Technology Process of 3-Bromo-6-fluoro-2-methylbenzonitrile

There total 2 articles about 3-Bromo-6-fluoro-2-methylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 198633-76-0
2-fluoro-6-methyl-benzonitrile

: 1255207-47-6
3-bromo-6-fluoro-2-methyl-benzonitrile

Guidance literature:: With N-Bromosuccinimide; trifluorormethanesulfonic acid; at 20 ℃; for 0.5h; Cooling with ice;

Reference yield:

: 883502-14-5
1-fluoro-2-iodo-3-methylbenzene

: 1255207-47-6
3-bromo-6-fluoro-2-methyl-benzonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / N,N-dimethyl acetamide / 16 h / 80 °C / Inert atmosphere

2: trifluorormethanesulfonic acid; N-Bromosuccinimide / 1 h / 0 - 20 °C

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; trifluorormethanesulfonic acid; In N,N-dimethyl acetamide;

Reference yield: 30.0%

: 1255207-47-6
3-bromo-6-fluoro-2-methyl-benzonitrile

: 10387-40-3
potassium thioacetate

: S-(3-cyano-4-fluoro-2-methyl-phenyl)ethanethioate

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; for 4.5h; Inert atmosphere; Reflux;