1-Hydroxy-3-iodonaphthalene

Base Information

• Chemical Name: 1-Hydroxy-3-iodonaphthalene
• CAS No.: 90800-20-7
• Molecular Formula: C10H7IO
• Molecular Weight: 270.06645
• Mol file: 90800-20-7.mol

Synonyms:1-Hydroxy-3-iodonaphthalene

Chemical Property of 1-Hydroxy-3-iodonaphthalene

Chemical Property:

• PSA: 20.23000
• LogP: 3.15000

Purity/Quality:

97% ^*data from raw suppliers

2-Iodo-4-naphthol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Hydroxy-3-iodonaphthalene

There total 5 articles about 1-Hydroxy-3-iodonaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C10H9IO2 → 3-iodo-1-naphthol (90800-20-7) + 1-(tert-butyldimethylsilyl)-4-(4',4',5',5'-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-5-ol (103027-41-4)

Guidance literature:

With perchloric acid; In water; acetonitrile; at 25 ℃; for 12h; Concentration; Kinetics;

DOI:10.1021/jo201591r

Reference yield:

3-iodo-[1]naphthylamine (90841-85-3) → 3-iodo-1-naphthol (90800-20-7)

Guidance literature:

With sulfuric acid; acetic acid; Diazotization_.Durchleiten von Wasserdampf;

DOI:10.1039/jr9340001705

Reference yield:

3-iodo-1-nitro-naphthalene (690226-82-5) → 3-iodo-1-naphthol (90800-20-7)

Guidance literature:

Multi-step reaction with 2 steps

1: tin (II)-chloride; aq.-ethanolic hydrochloric acid

2: glacial acetic acid; concentrated sulfuric acid / Diazotization_.Durchleiten von Wasserdampf

With hydrogenchloride; sulfuric acid; acetic acid; tin(ll) chloride;

DOI:10.1039/jr9340001705

upstream raw materials:

3-iodo-[1]naphthylamine

3-iodo-1-nitro-naphthalene

2-iodo-4-nitronaphthalen-1-ylamine

Refernces