Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]-

Base Information

Chemical Name:Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]-
CAS No.:374600-24-5
Molecular Formula:C15H14ClNO4
Molecular Weight:307.733
Hs Code.:
DSSTox Substance ID:DTXSID80450226
Wikidata:Q82269840
Mol file:374600-24-5.mol

Synonyms:374600-24-5;BENZENE, 2-CHLORO-1-NITRO-3-[2-(PHENYLMETHOXY)ETHOXY]-;DTXSID80450226;1-[2-(BENZYLOXY)ETHOXY]-2-CHLORO-3-NITROBENZENE

Suppliers and Price of Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]-

Chemical Property:

PSA：64.28000
LogP:4.36700
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:307.0611356
Heavy Atom Count:21
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCCOC2=CC=CC(=C2Cl)[N+](=O)[O-]

Technology Process of Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]-

There total 1 articles about Benzene, 2-chloro-1-nitro-3-[2-(phenylmethoxy)ethoxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 622-08-2,1201808-31-2
2-Benzyloxyethanol

: 603-84-9
2-chloro-3-nitrophenol

: 374600-24-5
1-(2-benzyloxyethoxy)-2-chloro-3-nitrobenzene

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 0 ℃; for 2h;
DOI:10.1021/jm0102304

Reference yield: 89.0%

: 31614-66-1
tributyl(p-tolyl)stannane

: 374600-24-5
1-(2-benzyloxyethoxy)-2-chloro-3-nitrobenzene

: 374600-26-7
2-(2-benzyloxyethoxy)-4'-methyl-6-nitrobiphenyl

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; In 1,4-dioxane; at 20 ℃; for 4h;
DOI:10.1021/jm0102304

Reference yield:

: 374600-24-5
1-(2-benzyloxyethoxy)-2-chloro-3-nitrobenzene

: 374600-28-9
4-tert-butyl-N-(3-(2-hydroxyethoxy)-2-(4-methylphenyl)phenyl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 4 steps

1: 89 percent / PdCl₂(PPh₃)2 / dioxane / 4 h / 20 °C

2: 87 percent / Fe; 10percent aq. HCl / ethanol / 3.5 h / Heating

3: 100 percent / pyridine / 2 h / 20 °C

4: 93 percent / H₂; H₂O / 10percent Pd/C / ethanol / 3 h / 20 °C

With pyridine; bis-triphenylphosphine-palladium(II) chloride; water; hydrogen; iron; 10percent Pd/C; In 1,4-dioxane; ethanol;
DOI:10.1021/jm0102304