(3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID

Base Information

• Chemical Name: (3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID
• CAS No.: 150188-64-0
• Molecular Formula: C10H13NO3
• Molecular Weight: 195.218
• Hs Code.: 2922509090
• Mol file: 150188-64-0.mol

Synonyms:(3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID;2-(3-(DiMethylaMino)phenoxy)acetic acid

Chemical Property of (3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID

Chemical Property:

• PSA: 49.77000
• LogP: 1.21600
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(3-(Dimethylamino)phenoxy)aceticAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID

There total 3 articles about (3-DIMETHYLAMINO-PHENOXY)-ACETIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 2-(4-(dimethylamino)phenoxy)acetate → 3-(dimethylamino)phenoxyacetic acid (150188-64-0)

Guidance literature:

With water; lithium hydroxide; In tetrahydrofuran;

DOI:10.1016/j.molstruc.2020.129173

Reference yield:

3-Dimethylaminophenol (99-07-0) → 3-(dimethylamino)phenoxyacetic acid (150188-64-0)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 5 h / 80 °C

2: H₂ / 5 percent Pd/C / methanol / 2 h

With hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; N,N-dimethyl-formamide;

DOI:10.1248/cpb.48.1310

Reference yield:

(3-dimethylamino-phenoxy)-acetic acid benzyl ester (305129-48-0) → 3-(dimethylamino)phenoxyacetic acid (150188-64-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 2h;

DOI:10.1248/cpb.48.1310

upstream raw materials:

(3-dimethylamino-phenoxy)-acetic acid benzyl ester

3-Dimethylaminophenol

Downstream raw materials:

2-(3-Dimethylamino-phenoxy)-N-dimethylcarbamoylmethyl-acetamide

2-(3-Dimethylamino-phenoxy)-N-methylcarbamoylmethyl-acetamide

(R)-N-tert-butyl-3-{(2S,3S)-2-hydroxy-3-[(S)-2-(3-dimethylaminophenoxyacetyl)amino-3-methylbutanoyl]amino-4-phenylbutanoyl}-5,5-dimethyl-1,3-thiazolidine-4-carboxamide

(S)-tert-butyl 2-(2-(3-(dimethylamino)phenoxy)acetamido)-4-methylpentanoate