4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate

Base Information

Chemical Name:4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate
CAS No.:101014-65-7
Molecular Formula:C23H24O12
Molecular Weight:492.436
Hs Code.:

Synonyms:4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate;4-Methyl-2-oxo-2H-1-benzopyran-7-yl beta-D-glucopyranosiduronic acid methyl ester triacetate

Suppliers and Price of 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-?Methyl-?2-?oxo-?2H-?1-?benzopyran-?7-?yl-β-?D-?glucopyranosiduronicAcidMethylEster2,3,4-Triacetate
5mg
$ 165.00

Medical Isotopes, Inc.
4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronicAcidMethylEster2,3,4-Triacetate
5 mg
$ 650.00

Total 2 raw suppliers

Chemical Property of 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate

Chemical Property:

Melting Point:189-190 °C
Boiling Point:589.6±50.0 °C(Predicted)
PSA：153.87000
Density:1.39±0.1 g/cm3(Predicted)
LogP:1.17320
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

95% ^*data from raw suppliers

4-?Methyl-?2-?oxo-?2H-?1-?benzopyran-?7-?yl-β-?D-?glucopyranosiduronicAcidMethylEster2,3,4-Triacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester is an protected metabolite of 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid (M334701), a fluorogenic substrate in the assay of a-L-Iduronidase and is useful in the detection of Hurlers syndrome.

Technology Process of 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate

There total 1 articles about 4-Methyl-2-oxo-2H-1-benzopyran-7-yl-β-D-glucopyranosiduronic Acid Methyl Ester 2,3,4-Triacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 90-33-5,79566-13-5
7-hydroxy-4-methyl-chromen-2-one

: 7355-18-2
(2S,3S,4S,5R,6S)-3,4,5,6-Tetraacetoxy-tetrahydro-pyran-2-carboxylic acid methyl ester

: 2747-05-9
4-methylumbelliferyl acetate

: 101014-65-7
methyl (4′-methylumbelliferyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)urinate

Guidance literature:: With dmap; boron trifluoride diethyl etherate; In 1,2-dichloro-ethane; at 60 ℃; for 5h; Temperature; stereoselective reaction; Inert atmosphere;
DOI:10.3390/molecules201219789

Reference yield: 89.0%

: 101014-65-7
methyl (4′-methylumbelliferyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)urinate

: 6160-80-1,84434-84-4
4-methylumbelliferyl-β-D-glucuronide

Guidance literature:: With water; potassium carbonate; In methanol; dichloromethane; at 0 - 5 ℃; for 12h;

Reference yield: 48.0%

: 101014-65-7
methyl (4′-methylumbelliferyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)urinate

: 116523-82-1,128095-52-3
methyl 4-methylcoumarin-7-yl-β-D-glucopyranuronate

: 128095-52-3
4-methylcoumarin-7-yl-α-L-iduronic acid methyl ester

Guidance literature:: methyl (4′-methylumbelliferyl 2,3,4-tri-O-acetyl-β-D-glucopyranosid)urinate; With N-Bromosuccinimide; In tetrachloromethane; for 2h; Inert atmosphere; Irradiation; Reflux;

With triethyl borane; tri-n-butyl-tin hydride; In hexane; dichloromethane; at -78 - 20 ℃; for 5h; Inert atmosphere;

With sodium methylate; In methanol; at 0 - 20 ℃; for 4.5h; Inert atmosphere;
DOI:10.1055/s-0040-1708021