3-Hydrazinylisoquinoline

Base Information

• Chemical Name: 3-Hydrazinylisoquinoline
• CAS No.: 67107-32-8
• Molecular Formula: C9H9N3
• Molecular Weight: 159.191
• DSSTox Substance ID: DTXSID20497877
• Wikidata: Q82347648
• Mol file: 67107-32-8.mol

Synonyms:67107-32-8;3-HYDRAZINYLISOQUINOLINE;SCHEMBL25242404;DTXSID20497877;MFCD08361729;SY356688

Chemical Property of 3-Hydrazinylisoquinoline

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 400.507°C at 760 mmHg
• Flash Point: 196.02°C
• PSA: 50.94000
• Density: 1.29g/cm³
• LogP: 2.29370
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 159.079647300
• Heavy Atom Count: 12
• Complexity: 149

Purity/Quality:

3-hydrazinoisoquinoline 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C=NC(=CC2=C1)NN

Technology Process of 3-Hydrazinylisoquinoline

There total 1 articles about 3-Hydrazinylisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-hydrazinoquinoline (67107-32-8)

Guidance literature:

N-Oxid 1, TiCl3;

Reference yield: 99.0%

4-Fluorobenzoic acid (456-22-4) + 2-hydrazinoquinoline (67107-32-8) → C16H10FN3

Guidance literature:

4-Fluorobenzoic acid; With 1,1'-carbonyldiimidazole; In acetonitrile; at 40 ℃; for 0.833333h; Inert atmosphere; Flow reactor;

2-hydrazinoquinoline; In acetonitrile; at 40 ℃; for 1.5h; Inert atmosphere; Flow reactor;

DOI:10.1021/acs.orglett.5b03589

Reference yield: 86.0%

2-hydrazinoquinoline (67107-32-8) + ethyl 3-oxo-3-phenylpropionate (94-02-0) → 5-hydroxy-3-phenyl-1-(3-isoquinolinyl)-1H-pyrazole (1262236-05-4)

Guidance literature:

In acetic acid; for 4h; Reflux; Inert atmosphere;

DOI:10.1002/jhet.442

Downstream raw materials:

5-hydroxy-3-phenyl-1-(3-isoquinolinyl)-1H-pyrazole