O-Arachidonoyl Glycidol

Base Information

• Chemical Name: O-Arachidonoyl Glycidol
• CAS No.: 439146-24-4
• Molecular Formula: C23H36O3
• Molecular Weight: 360.537
• DSSTox Substance ID: DTXSID50694034
• Mol file: 439146-24-4.mol

Synonyms:O-Arachidonoyl Glycidol;DTXSID50694034;CHEBI:177016;AKOS030242110;oxiran-2-ylmethyl icosa-5,8,11,14-tetraenoate;(Oxiran-2-yl)methyl icosa-5,8,11,14-tetraenoate

Chemical Property of O-Arachidonoyl Glycidol

Chemical Property:

• PSA: 38.83000
• LogP: 6.07410
• Storage Temp.: Amber Vial, -20°C Freezer
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)
• XLogP3: 6.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 17
• Exact Mass: 360.26644501
• Heavy Atom Count: 26
• Complexity: 460

Purity/Quality:

98%Min ^*data from raw suppliers

Arachidonic Acid Glycidyl Ester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)OCC1CO1
• Uses: Arachidonic Acid Glycidyl Ester is an ester derivative of the essential fatty acid Arachidonic Acid (A765000) and an intermediate in the preparation of the endocannabinoid 2-Arachidonyl Glycerol (A765050). Arachidonic Acid Glycidyl Ester has inhibitory activity against monoacylglycerol lipase and fatty acid amide hydrolase.

Technology Process of O-Arachidonoyl Glycidol

There total 1 articles about O-Arachidonoyl Glycidol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

all cis 5,8,11,14-eicosatetraenoic acid (506-32-1,236743-58-1) + oxiranyl-methanol (556-52-5) → oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate (439146-24-4)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1016/j.tet.2005.02.034

Reference yield:

oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate (439146-24-4) → 2-arachidonoyl glycerol (53847-30-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 94 percent / CH₂Cl₂ / -20 - 20 °C

2: 92 percent / pyridine; methanol / pentane; CH₂Cl₂ / 3 h / 20 °C

With pyridine; methanol; In dichloromethane; pentane;

DOI:10.1016/j.tet.2005.02.034

Reference yield:

oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate (439146-24-4) → 1,3-di-O-benzoyl-2-O-arachidonoylglycerol

Guidance literature:

Multi-step reaction with 3 steps

1: 94 percent / CH₂Cl₂ / -20 - 20 °C

2: 92 percent / pyridine; methanol / pentane; CH₂Cl₂ / 3 h / 20 °C

3: 86 percent / pyridine / CH₂Cl₂ / -20 - 20 °C

With pyridine; methanol; In dichloromethane; pentane;

DOI:10.1016/j.tet.2005.02.034

upstream raw materials:

all cis 5,8,11,14-eicosatetraenoic acid

oxiranyl-methanol

Downstream raw materials:

2-arachidonoyl glycerol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 439146-24-4 O-ARACHIDONOYL GLYCIDOL

Send

Send

Metric Ton KG G Pound L ML

Send

Send