1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid

Base Information

Chemical Name:1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid
CAS No.:191873-41-3
Molecular Formula:C₂₂H₂₆FN₃O₈
Molecular Weight:479.462
Hs Code.:
Mol file:191873-41-3.mol

Synonyms:1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid;Retigabine N-β-D-Glucuronide;Retigabine N-β-D-Glucuronide SodiuM Salt

Suppliers and Price of 1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
RetigabineN-β-D-GlucuronideSodiumSalt
10mg
$ 1390.00

Total 1 raw suppliers

Chemical Property of 1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid

Chemical Property:

PSA：173.10000
LogP:1.46990
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:DMSO (Slightly), Methanol (Slightly), Water (Slightly)

Purity/Quality:: RetigabineN-β-D-GlucuronideSodiumSalt ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Retigabine N-β-D-Glucuronide is the major metabolite of the antiepileptic drug Retigabine (R189050) that is produced via N-glucuronidation in humans. Sodium salt of Retigabine N-β-D-Glucuronide is the major metabolite of the antiepileptic drug Retigabine (R189050) that is produced via N-glucuronidation in humans.

Technology Process of 1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid

There total 1 articles about 1-Deoxy-1-[[2-[(ethoxycarbonyl)aMino]-5-[[(4-fluorophenyl)Methyl]aMino]phenyl]aMino] β-D-Glucopyranuronic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2616-64-0
UDP-glucuronic acid

: 150812-12-7
Retigabine

: 191873-41-3
retigabine N-β-D-glucuronide

: (2S,3S,4S,5R,6R)-6-[(3-Amino-4-ethoxycarbonylamino-phenyl)-(4-fluoro-benzyl)-amino]-3,4,5-trihydroxy-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: With human liver microsomes; In dimethyl sulfoxide; at 37 ℃; for 2h; pH=8.0; Further Variations:; Reagents; Enzyme kinetics;
DOI:10.1080/004982597240424