3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID

Base Information

• Chemical Name: 3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID
• CAS No.: 41819-13-0
• Molecular Formula: C10H4Br2O8
• Molecular Weight: 411.945
• Mol file: 41819-13-0.mol

Synonyms:3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID;3,6-dibromopyromellitic acid;3,6-Dibrom-benzol-1,2,4,5-tetracarbonsaeure;3,6-Dibromobenzene-1,2,4,5-tetracarboxylic acid

Chemical Property of 3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID

Chemical Property:

• Boiling Point: 576.9±50.0 °C(Predicted)
• PKA: 0.13±0.10(Predicted)
• PSA: 149.20000
• Density: 2.396±0.06 g/cm3(Predicted)
• LogP: 2.00440
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3,6-Dibromobenzene-1,2,4,5-tetracarboxylicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID

There total 7 articles about 3,6-DIBROMO-1,2,4,5-BENZENETETRACARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Pyromellitic dianhydride (89-32-7,34527-94-1) → 3,6-di-bromo-1,2,4,5-benzenetetracarboxylic acid (41819-13-0)

Guidance literature:

With water; bromine; sodium hydroxide; at 50 ℃; for 2h; Reagent/catalyst; Inert atmosphere; Darkness;

Reference yield: 83.0%

1,4-dibromodurene (1646-54-4) → 3,6-di-bromo-1,2,4,5-benzenetetracarboxylic acid (41819-13-0)

Guidance literature:

With potassium permanganate; In water; tert-butyl alcohol; Reflux;

DOI:10.1039/c4sc00999a

Reference yield:

1,2,4,5-tetramethylbenzene (95-93-2) → 3,6-di-bromo-1,2,4,5-benzenetetracarboxylic acid (41819-13-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / Br₂, Al / CHCl₃ / 2 h / 15 - 20 °C

2: 25percent HNO₃, NH₄VO₃, 2.) KMnO₄, KOH / 1.) 180 deg C, 20 h, 2.) H₂O, reflux, 20 h

With ammonium metavanadate; potassium hydroxide; potassium permanganate; bromine; nitric acid; aluminium; In chloroform;

upstream raw materials:

1,4-dibromo-2,5-diethyl-3,6-dimethylbenzene

1,4-dibromodurene

1,2,4,5-tetramethylbenzene

1,4-diethyl-2,5-dimethyl-benzene

Downstream raw materials:

C₄₂H₄₄N₂O₄

C₄₄H₄₈N₂O₆

C₄₆H₅₄N₄O₄