Tert-butyl 2-(4-bromophenyl)acetate

Base Information

• Chemical Name: Tert-butyl 2-(4-bromophenyl)acetate
• CAS No.: 33155-58-7
• Molecular Formula: C12H15BrO2
• Molecular Weight: 271.154
• Hs Code.: 2916399090
• European Community (EC) Number: 877-668-2
• Nikkaji Number: J3.271.520F
• Mol file: 33155-58-7.mol

Synonyms:TERT-BUTYL 2-(4-BROMOPHENYL)ACETATE;33155-58-7;MFCD11975535;tert-Butyl2-(4-Bromophenyl)acetate;Benzeneacetic acid, 4-bromo-, 1,1-dimethylethyl ester;SCHEMBL5533824;ZMSZCAZHKBNPDV-UHFFFAOYSA-N;tert-Butyl (4-bromophenyl)acetate;AMY32251;Tert-Butyl 2-(4-Bromophenyl)acetat;AKOS013210849;CS-11565;SY025134;CS-0154836;EN300-1692827;A875408;Benzeneacetic acid,4-bromo-,1,1-dimethylethyl ester

Chemical Property of Tert-butyl 2-(4-bromophenyl)acetate

Chemical Property:

• Boiling Point: 305.7±17.0 °C(Predicted)
• Density: 1.303±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 270.02554
• Heavy Atom Count: 15
• Complexity: 212

Purity/Quality:

98% ^*data from raw suppliers

tert-Butyl2-(4-Bromophenyl)acetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)CC1=CC=C(C=C1)Br
• Uses: tert-Butyl 2-(4-Bromophenyl)acetate is used as a reactant in the preparation of thiophene-containing biaryl amide derivatives as glucagon receptor antagonists.

Technology Process of Tert-butyl 2-(4-bromophenyl)acetate

There total 10 articles about Tert-butyl 2-(4-bromophenyl)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

tert-butyl acetoacetate (1694-31-1) + 1,4-bromoiodobenzene (589-87-7) → tert-butyl 2-(4-bromophenyl)acetate (33155-58-7)

Guidance literature:

With 2-Picolinic acid; copper(l) iodide; caesium carbonate; In 1,4-dioxane; at 70 ℃; Inert atmosphere;

DOI:10.1016/j.tet.2013.10.017

Reference yield: 85.0%

di-tert-butyl dicarbonate (24424-99-5) + 2-(4-bromophenyl)-acetic acid (1878-68-8) → tert-butyl 2-(4-bromophenyl)acetate (33155-58-7)

Guidance literature:

With dmap; In tert-butyl alcohol;

DOI:10.1016/j.bmcl.2021.128354

Reference yield: 78.0%

tert-Butyl 2,2,2-trichloroacetimidate (98946-18-0) + 2-(4-bromophenyl)-acetic acid (1878-68-8) → tert-butyl 2-(4-bromophenyl)acetate (33155-58-7)

Guidance literature:

With boron trifluoride diethyl etherate; In tetrahydrofuran; at 20 ℃; for 16h;

upstream raw materials:

acetic acid tert-butyl ester

2-(4-bromophenyl)-acetic acid

tert-Butyl 2,2,2-trichloroacetimidate

N,N-dimethylformamide di-tert-butyl acetal

Downstream raw materials:

4-<(tert-buthoxycarbonyl)methyl>-β-N-phthalimidostyrene

butyl 4-(2-tert-butoxy-2-oxoethyl)benzoate

tert-butyl α-(para-bromophenyl)diazoacetate

{4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethyl]-phenyl}-acetic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 33155-58-7 tert-butyl 2-(4-bromophenyl)acetate

Send

Send

Metric Ton KG G Pound L ML

Send

Send