(4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE

Base Information

• Chemical Name: (4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE
• CAS No.: 1059626-05-9
• Molecular Formula: C7H10ClFN2
• Molecular Weight: 176.62
• Hs Code.: 2928000090
• Mol file: 1059626-05-9.mol

Synonyms:(4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE;1-Fluoro-4-(hydrazinomethyl)benzene hydrochloride

Chemical Property of (4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE

Chemical Property:

• PSA: 38.05000
• LogP: 2.68220
• Storage Temp.: Store Cold

Purity/Quality:

98%,99%, ^*data from raw suppliers

(4-Fluorobenzyl)hydrazineHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C,Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE

There total 1 articles about (4-FLUOROBENZYL)HYDRAZINE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-1-(tert-butoxycarbonyl)-N-2-<(4-fluorophenyl)methyl>hydrazine (149267-65-2) → (4-fluorobenzyl)-hydrazine hydrochloride (1059626-05-9,1000805-93-5)

Guidance literature:

With hydrogenchloride; In ethanol; for 8h;

DOI:10.1016/j.ejmech.2012.04.020

Reference yield: 70.0%

(4-fluorobenzyl)-hydrazine hydrochloride (1059626-05-9,1000805-93-5) + benzyl [(1Z)-{[(2,4-dichlorophenyl)acetyl]amino}(methylthio)methylene]carbamate (1142400-41-6) → 5-(2,4-dichloro-benzyl)-1-(4-fluoro-benzyl)-1-H-[1,2,4]triazol-3-ylamine (1142400-17-6)

Guidance literature:

With triethylamine; at 160 ℃; for 0.5h; Microwave irradiation;

DOI:10.1016/j.tetlet.2008.12.042

Reference yield: 56.0%

C16H20N2O3S (1142400-45-0) + (4-fluorobenzyl)-hydrazine hydrochloride (1059626-05-9,1000805-93-5) → C14H17FN4 (1142400-23-4)

Guidance literature:

With triethylamine; at 160 ℃; for 0.5h; Microwave irradiation;

DOI:10.1016/j.tetlet.2008.12.042

upstream raw materials:

N-1-(tert-butoxycarbonyl)-N-2-<(4-fluorophenyl)methyl>hydrazine

Downstream raw materials:

5-(2,4-dichloro-benzyl)-1-(4-fluoro-benzyl)-1-H-[1,2,4]triazol-3-ylamine

C₁₂H₁₅FN₄

C₁₄H₁₇FN₄

C₁₄H₁₂FN₅

Refernces