6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine

Base Information

Chemical Name:6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine
CAS No.:137057-67-1
Molecular Formula:C27H26N4O7
Molecular Weight:518.52
Hs Code.:
Mol file:137057-67-1.mol

Synonyms:6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine;9-[2-O,3-O-Bis(phenylacetyl)-β-D-arabinofuranosyl]-6-methoxy-9H-purine

Suppliers and Price of 6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine

Chemical Property:

Boiling Point:718.6±70.0 °C(Predicted)
PKA:14.44±0.10(Predicted)
PSA：134.89000
Density:1.41±0.1 g/cm3(Predicted)
LogP:2.03360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine

There total 4 articles about 6-Methoxy-9-[2-O,3-O-bis(phenylacetyl)-β-D-arabinofuranosyl]-9H-purine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 137057-94-4
Phenyl-acetic acid (2R,3S,4R,5R)-5-(tert-butyl-dimethyl-silanyloxymethyl)-2-(6-methoxy-purin-9-yl)-4-phenylacetoxy-tetrahydro-furan-3-yl ester

: 137057-67-1
Phenyl-acetic acid (2R,3S,4R,5R)-5-hydroxymethyl-2-(6-methoxy-purin-9-yl)-4-phenylacetoxy-tetrahydro-furan-3-yl ester

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 5 ℃; for 1h; Yield given;
DOI:10.1021/jm00079a006

Reference yield:

: 1555-80-2
phenylacetic anhydride

: 137057-67-1
Phenyl-acetic acid (2R,3S,4R,5R)-5-hydroxymethyl-2-(6-methoxy-purin-9-yl)-4-phenylacetoxy-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / acetonitrile / 5 °C

2: aq. Bu₄NF / tetrahydrofuran / 1 h / 5 °C

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm00079a006

Reference yield:

: 9-<5-O-(tert-butyldimethylsilyl)-β-D-arabinofuranosyl>-6-methoxy-9H-purine

: 137057-67-1
Phenyl-acetic acid (2R,3S,4R,5R)-5-hydroxymethyl-2-(6-methoxy-purin-9-yl)-4-phenylacetoxy-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / acetonitrile / 5 °C

2: aq. Bu₄NF / tetrahydrofuran / 1 h / 5 °C

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran; acetonitrile;
DOI:10.1021/jm00079a006