Budesonide-d8

Base Information

Chemical Name:Budesonide-d8
CAS No.:1105542-94-6
Molecular Formula:C₂₅H₃₄O₆
Molecular Weight:438.478
Hs Code.:
DSSTox Substance ID:DTXSID801114046
Mol file:1105542-94-6.mol

Synonyms:Budesonide-d8;1105542-94-6;(1S,2S,4R,8S,9S,11S,12S,13R)-6-Deuterio-6-(1,1,2,2,3,3,3-heptadeuteriopropyl)-11-hydroxy-8-(2-hydroxyacetyl)-9,13-dimethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one;SCHEMBL13618426;DTXSID801114046;HY-13580S;AKOS037652739;ES-2500;CS-0202488;(11beta,16alpha)-16,17-[Butylidene-1,2,2,3,3,4,4,4-d8-bis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione

Suppliers and Price of Budesonide-d8

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Budesonide-d8
1mg
$ 180.00

Medical Isotopes, Inc.
Budesonide-d8
5 mg
$ 2000.00

Chemtos
Budesonide-Labeledd8
10 mg
$ 1400.00

Cayman Chemical
Budesonide-d8
1mg
$ 275.00

American Custom Chemicals Corporation
BUDESONIDE-D8 95.00%
10MG
$ 1732.50

American Custom Chemicals Corporation
BUDESONIDE-D8 95.00%
1MG
$ 721.88

Total 7 raw suppliers

Chemical Property of Budesonide-d8

Chemical Property:

Melting Point:228-236°C dec.
PSA：93.06000
LogP:2.71680
Storage Temp.:-20°C Freezer
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:438.28575277
Heavy Atom Count:31
Complexity:862

Purity/Quality:

97% ^*data from raw suppliers

Budesonide-d8 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC1OC2CC3C4CCC5=CC(=O)C=CC5(C4C(CC3(C2(O1)C(=O)CO)C)O)C
Isomeric SMILES:[2H]C1(O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@@]5([C@H]4[C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)C)C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
Uses Budesonide-d8, a non-halogenated glucocorticoid related to triamcinolone hexacetonide, can be used as an antiinflammatory agent

Technology Process of Budesonide-d8

There total 2 articles about Budesonide-d8 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 1105542-94-6
[22,23,23,24,24,25,25,25-2H8]-16α,17α-(butylidenedioxy)-11β,21-dihydroxypregna-1,4,23-triene-3,20-dione

Guidance literature:

Reference yield:

: 84965-36-6
[D₈]-n-butanal

: 13951-70-7
desonide

: 1195763-25-7
[23,23,24,24,25,25,25-2H7]-16α,17α-(butylidenedioxy)-11β,21-dihydroxypregna-1,4,23-triene-3,20-dione

: 1105542-94-6
[22,23,23,24,24,25,25,25-2H8]-16α,17α-(butylidenedioxy)-11β,21-dihydroxypregna-1,4,23-triene-3,20-dione

Guidance literature:: With perchloric acid; In 1,4-dioxane; at 20 ℃; for 1h; Title compound not separated from byproducts.;
DOI:10.1002/jlcr.1480