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vorapaxar sulfate M-9

Base Information
  • Chemical Name:vorapaxar sulfate M-9
  • CAS No.:900161-11-7
  • Molecular Formula:C29H32N2O5
  • Molecular Weight:488.583
  • Hs Code.:
  • Mol file:900161-11-7.mol
vorapaxar sulfate M-9

Synonyms:vorapaxar sulfate M-9;Carbamic acid, [(1R,3aR,6R,8aS,9S,9aS)-9-[(diphenylamino)carbonyl]-1,3,3a,5,6,7,8,8a,9,9a-decahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl este

Suppliers and Price of vorapaxar sulfate M-9
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
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Total 7 raw suppliers
Chemical Property of vorapaxar sulfate M-9
Chemical Property:
Purity/Quality:

98%Min *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description Vorapaxar sulfate M-9 is a novel antiplatelet agent indicated for the treatment and prevention of atherothrombosis.
  • Mechanism of Action Vorapaxar sulfate M-9 is a novel protease-activated receptor 1 (PAR-1) antagonist that is orally effective and highly selective and can inhibit thrombin-induced platelet aggregation.
Technology Process of vorapaxar sulfate M-9

There total 23 articles about vorapaxar sulfate M-9 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.7%

Guidance literature:
In o-xylene; at 137 - 143 ℃; for 16h;
Guidance literature:
C27H28N2O4; With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere; Reflux;
chloroformic acid ethyl ester; With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere;
Guidance literature:
With 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1-methyl-pyrrolidin-2-one; at 40 - 140 ℃; for 16h;
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