4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile

Base Information

Chemical Name:4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile
CAS No.:1225383-63-0
Molecular Formula:C₁₃H₉Cl₂N₃O
Molecular Weight:294.14
Hs Code.:
Mol file:1225383-63-0.mol

Synonyms:4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile

Suppliers and Price of 4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile

There total 2 articles about 4-[(2,6-dichloro-4-pyrimidinyl)oxy]-3,5-dimethylbenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.5%

: 3764-01-0
2,4,6-trichloropyrimidine

: 4198-90-7
3,5-dimethyl-4-hydroxybenzonitrile

: 1225383-63-0
4-[(2,6-dichloro)-4-pyrimidinyloxy]-3,5-dimethylbenzonitrile

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; at 70 ℃; for 2h;

Reference yield:

: 3764-01-0
2,4,6-trichloropyrimidine

: 4198-90-7
3,5-dimethyl-4-hydroxybenzonitrile

: 1225383-63-0
4-[(2,6-dichloro)-4-pyrimidinyloxy]-3,5-dimethylbenzonitrile

: 1263409-98-8
4-(4,6-dichloropyrimidin-2-yloxy)-3,5-dimethylbenzonitrile

Guidance literature:: With sodium hydroxide; In water; acetone; at 3 - 30 ℃;

Reference yield: 62.0%

: 1225383-63-0
4-[(2,6-dichloro)-4-pyrimidinyloxy]-3,5-dimethylbenzonitrile

: 53312-80-4
4-amino-2-fluorobenzonitrile

: 4-((6-chloro-2-((4-cyano-3-fluorophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In 1,4-dioxane; at 120 ℃; for 12h; Inert atmosphere; Schlenk technique;
DOI:10.1021/acs.jmedchem.9b01769