daprodustat,GSK1278863

Base Information

Chemical Name:daprodustat,GSK1278863
CAS No.:960539-70-2
Molecular Formula:C₁₉H₂₇N₃O₆
Molecular Weight:393.44
Hs Code.:
Mol file:960539-70-2.mol

Synonyms:daprodustat,GSK1278863;GSK1278863;Daprodustat;2-(1,3-dicyclohexyl-2,4,6-trioxohexahydropyrimidine-5-carboxamido)acetic acid;N-[(1,3-Dicyclohexylhexahydro-2,4,6-trioxo-5-pyrimidinyl)carbonyl]glycine

Suppliers and Price of daprodustat,GSK1278863

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Daprodustat
10mg
$ 90.00

DC Chemicals
Daprodustat >98%
1 g
$ 1700.00

DC Chemicals
Daprodustat >98%
250 mg
$ 800.00

DC Chemicals
Daprodustat >98%
100 mg
$ 450.00

Crysdot
Daprodustat 98+%
5mg
$ 74.00

Crysdot
Daprodustat 98+%
25mg
$ 248.00

ChemScene
Daprodustat 99.39%
100mg
$ 650.00

ChemScene
Daprodustat 99.39%
50mg
$ 380.00

ChemScene
Daprodustat 99.39%
25mg
$ 225.00

ChemScene
Daprodustat 99.39%
10mg
$ 135.00

Total 71 raw suppliers

Chemical Property of daprodustat,GSK1278863

Chemical Property:

PKA:3.44±0.10(Predicted)
PSA：124.09000
Density:1.359±0.06 g/cm3(Predicted)
LogP:1.52630
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

Daprodustat ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Daprodustat is a novel HIF (Hypoxia inducible factor)-prolyl hydroxylase inhibitor.

Technology Process of daprodustat,GSK1278863

There total 3 articles about daprodustat,GSK1278863 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₁H₃₁N₃O₆

: 960539-70-2
GSK-1278863A

Guidance literature:: With ethanol; sodium hydroxide; at 20 ℃; for 3h;

Reference yield:

: 2387-23-7
1,3-Dicyclohexylurea

: 960539-70-2
GSK-1278863A

Guidance literature:: Multi-step reaction with 3 steps

1: chloroform / 4.5 h / 50 °C / Inert atmosphere

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

3: sodium hydroxide; ethanol / 3 h / 20 °C

With ethanol; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In dichloromethane; chloroform;

Reference yield:

: 35824-91-0
1,3-dicyclohexyl barbituric acid

: 960539-70-2
GSK-1278863A

Guidance literature:: Multi-step reaction with 2 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

2: sodium hydroxide; ethanol / 3 h / 20 °C

With ethanol; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In dichloromethane;