2-Oxoindoline-3-carbonitrile

Base Information

Chemical Name:2-Oxoindoline-3-carbonitrile
CAS No.:73859-65-1
Molecular Formula:C₉H₆N₂O
Molecular Weight:158.159
Hs Code.:2933790090
DSSTox Substance ID:DTXSID60547168
Mol file:73859-65-1.mol

Synonyms:2-Oxoindoline-3-carbonitrile;73859-65-1;2-OXO-1,3-DIHYDROINDOLE-3-CARBONITRILE;2-oxindole-3-carbonitrile;2-Oxo-2,3-dihydro-1H-indole-3-carbonitrile;DTXSID60547168;SB65288

Suppliers and Price of 2-Oxoindoline-3-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Oxoindoline-3-carbonitrile 95+%
1g
$ 762.00

Chemenu
2-oxoindoline-3-carbonitrile 95%
1g
$ 720.00

Alichem
2-Oxoindoline-3-carbonitrile
1g
$ 620.00

AccelPharmtech
2,3-dihydro-2-oxo-1H-Indole-3-carbonitrile 97.00%
25G
$ 5120.00

AccelPharmtech
2,3-dihydro-2-oxo-1H-Indole-3-carbonitrile 97.00%
5G
$ 2750.00

Total 4 raw suppliers

Chemical Property of 2-Oxoindoline-3-carbonitrile

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:399.379°C at 760 mmHg
Flash Point:195.338°C
PSA：56.38000
Density:1.323g/cm³
LogP:1.33098
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:158.048012819
Heavy Atom Count:12
Complexity:253

Purity/Quality:

95% ^*data from raw suppliers

2-Oxoindoline-3-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C(=O)N2)C#N

Technology Process of 2-Oxoindoline-3-carbonitrile

There total 4 articles about 2-Oxoindoline-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 2-cyano-2-diazo-N,N-diphenylacetamide

: 73859-65-1
2-oxo-1-phenylindoline-3-carbonitrile

Guidance literature:: With rhodium (II) octanoate dimer; In dichloromethane; for 2h; Reflux;
DOI:10.1002/adsc.201600118

Reference yield:

: 51838-06-3
3-(N,N-diphenylamino)-3-oxopropanenitrile

: 73859-65-1
2-oxo-1-phenylindoline-3-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; triflic azide / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere; Cooling with ice

2: rhodium (II) octanoate dimer / dichloromethane / 2 h / Reflux

With rhodium (II) octanoate dimer; triflic azide; triethylamine; In dichloromethane;
DOI:10.1002/adsc.201600118

Reference yield:

: 122-39-4
diphenylamine

: 73859-65-1
2-oxo-1-phenylindoline-3-carbonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 1,3-Diphenylcarbodiimide; dmap / dichloromethane / 1 h / 0 °C

2: triethylamine; triflic azide / dichloromethane / 18 h / 0 - 20 °C / Inert atmosphere; Cooling with ice

3: rhodium (II) octanoate dimer / dichloromethane / 2 h / Reflux

With dmap; rhodium (II) octanoate dimer; triflic azide; triethylamine; 1,3-Diphenylcarbodiimide; In dichloromethane;
DOI:10.1002/adsc.201600118