1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE

Base Information

Chemical Name:1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE
CAS No.:869308-34-9
Molecular Formula:C₁₄H₃₂N₂O₅
Molecular Weight:308.418
Hs Code.:2922190090
Mol file:869308-34-9.mol

Synonyms:1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE;4,7,10,13,16-Pentaoxanonadecane-1,19-diamine

Suppliers and Price of 1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE 95.00%
5MG
$ 505.67

Total 8 raw suppliers

Chemical Property of 1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE

Chemical Property:

PSA：98.19000
LogP:1.16760

Purity/Quality:

99.3% ^*data from raw suppliers

1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description 4,7,10,13,16-Pentaoxanonadecane-1,19-diamine is a PEG based linker with two terminal amine groups. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
Uses 4,7,10,13,16-Pentaoxanonadecane-1,19-diamine is used in the synthesis of bivalent ligands for adenosine A1-?dopamine D1 receptor heteromers (A1-?D1R)?, and in evaluating their pharmacological properties.

Technology Process of 1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE

There total 2 articles about 1,19-DIAMINO-4,7,10,13,16-PENTAOXA-NONADECANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 41263-79-0
4,7,10,13,16-pentaoxanonadecane-1,14-dinitrile

: 869308-34-9
1,19-diamino-4,7,10,13,16-pentaoxanonadecane

Guidance literature:: 4,7,10,13,16-pentaoxanonadecane-1,14-dinitrile; With borane-THF; In tetrahydrofuran; Reflux;

With hydrogenchloride; In tetrahydrofuran; methanol; water; at 20 ℃;
DOI:10.1246/bcsj.80.1703

Reference yield:

: 112-60-7
Tetraethylene glycol

: 869308-34-9
1,19-diamino-4,7,10,13,16-pentaoxanonadecane

Guidance literature:: Multi-step reaction with 2 steps

1: potassium hydroxide / tetrahydrofuran / 1.5 h / 20 °C

2: borane-THF / tetrahydrofuran / 4 h / 0 °C / Inert atmosphere; Reflux

With borane-THF; potassium hydroxide; In tetrahydrofuran; 1: |Michael Addition;
DOI:10.1038/aps.2012.151

Reference yield:

: 869308-34-9
1,19-diamino-4,7,10,13,16-pentaoxanonadecane

: (4-(21((2-carbamoyl-5-(3,6,6-trimethyl-4-oxo-4,5,6,7-tetrahydro-1H-1-yl)phenyl)amino)-6,9,12,15,18-pentaoxa-2-azahenicosyl)phenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-ethyl-N,N-diisopropylamine / dimethylsulfoxide-d6 / 0.33 h / 90 °C

1.2: 90 °C

2.1: sodium tris(acetoxy)borohydride; acetic acid / 1,2-dichloro-ethane / 24 h

With sodium tris(acetoxy)borohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In dimethylsulfoxide-d6; 1,2-dichloro-ethane;