2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE

Base Information

• Chemical Name: 2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE
• CAS No.: 773135-43-6
• Molecular Formula: C10H8ClF3O2
• Molecular Weight: 252.621
• Mol file: 773135-43-6.mol

Synonyms:2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE;ETHYL 2-CHLORO-3-(TRIFLUOROMETHYL)BENZOATE;RARECHEM AL BI 0475

Chemical Property of 2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE

Chemical Property:

• PSA: 26.30000
• LogP: 3.53550

Purity/Quality:

98%min ^*data from raw suppliers

ETHYL 2-CHLORO-3-(TRIFLUOROMETHYL)BENZOATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE

There total 1 articles about 2-CHLORO-3-TRIFLUOROMETHYL ETHYL BENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 2-chloro-3-trifluoromethylbenzoic acid (39226-97-6) → ethyl 2-chloro-3-(trifluoromethyl)benzoate (773135-43-6)

Guidance literature:

With sulfuric acid; for 24h; Heating / reflux;

Reference yield: 83.0%

ethyl 2-chloro-3-(trifluoromethyl)benzoate (773135-43-6) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → ethyl 2-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(trifluoromethyl)benzoate

Guidance literature:

With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; at 80 ℃; for 24h; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0037-1610538

Reference yield:

ethyl 2-chloro-3-(trifluoromethyl)benzoate (773135-43-6) → 2-chloro-3-(trifluoromethyl)benzohydrazide

Guidance literature:

With hydrazine; In ethanol; for 3h;

upstream raw materials:

ethanol

2-chloro-3-trifluoromethylbenzoic acid

Refernces