6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene

Base Information

• Chemical Name: 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene
• CAS No.: 206434-85-7
• Molecular Formula: C₃₀H₃₁NO₅S₂
• Molecular Weight: 549.712

Synonyms:6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene

Chemical Property of 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene

There total 5 articles about 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(4'-methoxyphenyl)-6-methoxybenzothiophene (63675-74-1) + 4-(2-(piperidin-1-yl)ethyl)sulfonylbenzoic acid (206434-83-5) → 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene (206434-85-7)

Guidance literature:

With thionyl chloride; sodium hydrogencarbonate; aluminium trichloride; In N-methyl-acetamide; methanol; MeCl₂; dichloromethane; water; ethyl acetate; toluene;

Reference yield:

2-(4'-methoxyphenyl)-6-methoxybenzothiophene (63675-74-1) + 4-(2-piperidin-1-yl-ethanesulfonyl)-benzoyl chloride (206434-84-6) → 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene (206434-85-7)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-ethane; at 5 - 23 ℃; Yield given;

DOI:10.1016/S0960-894X(99)00050-5

Reference yield:

piperidine (110-89-4) → 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene (206434-85-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 58 percent / dimethylformamide / 1 h / 120 °C

2: SOCl₂

3: AlCl₃ / 1,2-dichloro-ethane / 5 - 23 °C

With aluminium trichloride; thionyl chloride; In 1,2-dichloro-ethane; N,N-dimethyl-formamide;

DOI:10.1016/S0960-894X(99)00050-5

upstream raw materials:

2-(4'-methoxyphenyl)-6-methoxybenzothiophene

4-(2-piperidin-1-yl-ethanesulfonyl)-benzoyl chloride

piperidine

4-(2-Chloroethylsulfonyl)-benzoic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 206434-85-7 6-methoxy-2-(4-methoxyphenyl)-3-[4-(2-(piperidin-1-yl)ethylsulfonyl)benzoyl]benzo[b]thiophene

Send

Send

Metric Ton KG G Pound L ML

Send

Send