N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide

Base Information

• Chemical Name: N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide
• CAS No.: 1231951-34-0
• Molecular Formula: C₁₉H₂₉N₃O₄
• Molecular Weight: 363.457
• Mol file: 1231951-34-0.mol

Synonyms:N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide

Chemical Property of N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide

There total 1 articles about N-α-benzoyl-N₅-(tert-butoxycarbonyl)-L-ornithine ethyl amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

N-α-benzoyl-N5-(tert-butoxycarbonyl)-L-ornithine (1043444-25-2) + ethylamine (75-04-7,85404-22-4) → N-α-benzoyl-N5-(tert-butoxycarbonyl)-L-ornithine ethyl amide (1231951-34-0)

Guidance literature:

With triethylamine; S-(1-oxido-2-pyridyl)-thio-N,N,N',N'-tetramethyluronium hexafluorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃; for 0.75h;

DOI:10.1021/bi100363t

Reference yield: 94.0%

N-α-benzoyl-N5-(tert-butoxycarbonyl)-L-ornithine ethyl amide (1231951-34-0) → N-α-benzoyl-L-ornithine ethyl amide (1231951-35-1)

Guidance literature:

With trifluoroacetic acid; at 0 - 20 ℃;

DOI:10.1021/bi100363t

Reference yield:

N-α-benzoyl-N5-(tert-butoxycarbonyl)-L-ornithine ethyl amide (1231951-34-0) → C16H25ClN4O

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic acid / 0 - 20 °C

2: caesium carbonate / methanol / 16 h / 20 °C

With caesium carbonate; trifluoroacetic acid; In methanol;

DOI:10.1021/bi100363t

upstream raw materials:

N-α-benzoyl-N⁵-(tert-butoxycarbonyl)-L-ornithine

ethylamine

Downstream raw materials:

N-α-benzoyl-L-ornithine ethyl amide