{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

Base Information

Chemical Name:{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane
CAS No.:1352306-41-2
Molecular Formula:C₃₅H₄₀F₃IO₆Si
Molecular Weight:768.684
Hs Code.:

Synonyms:{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

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Chemical Property of {2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

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Technology Process of {2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

There total 1 articles about {2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1352306-42-3
2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]chroman-4-one

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 1352306-41-2
{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

Guidance literature:: With cesium fluoride; In 1,2-dimethoxyethane; at 20 ℃; for 24h;

Reference yield:

: 1352306-41-2
{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

: 1352306-43-4
3-(4-hydroxyphenyl)-2-(4-iodophenyl)-4-(trifluoromethyl)chroman-4,6-diol

Guidance literature:: With hydrogenchloride; water; In methanol; at 20 ℃; for 4h;

Reference yield:

: 1352306-41-2
{2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-chroman-4-yloxy}trimethyl-silane

: 1352306-40-1
2-(4-iodo-phenyl)-6-(tetrahydro-pyran-2-yloxy)-3-[4-(tetrahydro-pyran-2-yloxy)phenyl]-4-trifluoromethyl-2H-chromene

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogenchloride; water / methanol / 4 h / 20 °C

2: toluene-4-sulfonic acid / toluene / 18 h / Reflux

3: pyridinium p-toluenesulfonate / dichloromethane / 16 h / 30 °C

With hydrogenchloride; water; toluene-4-sulfonic acid; pyridinium p-toluenesulfonate; In methanol; dichloromethane; toluene;