Technology Process of 1-<9-(Benzoyloxy)-5,5-(ethylenedioxy)nonanethioyl>azacyclopentane
There total 10 articles about 1-<9-(Benzoyloxy)-5,5-(ethylenedioxy)nonanethioyl>azacyclopentane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
toluene-4-sulfonic acid;
In
benzene;
for 1h;
Heating;
removal of water;
DOI:10.1021/jo01298a022
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 82 percent / benzene
2: oxalyl chloride, Me2SO, triethylamine
3: magnesium, water
4: 87 percent / pyridine / CH2Cl2 / 1.) addition over 2 min, -78 deg C, 2.) 0 deg C, 2.5 h
5: 1.) hydrochloric acid, 2.) water
6: 95 percent / pyridine / CH2Cl2
7: 75 percent / phosphorus pentasulfide, triethylamine / CH2Cl2
8: 93 percent / zinc dust, glacial acetic acid / 1.5 h / Ambient temperature
9: 27 percent / aluminum isopropoxide / acetone; benzene
10: 90 percent / p-toluenesulfonic acid monohydrate / benzene / 1 h / Heating; removal of water
With
pyridine; hydrogenchloride; diphosphorus pentasulfide; oxalyl dichloride; water; aluminum isopropoxide; toluene-4-sulfonic acid; magnesium; acetic acid; dimethyl sulfoxide; triethylamine; zinc;
In
dichloromethane; acetone; benzene;
DOI:10.1021/jo01298a022
- Guidance literature:
-
Multi-step reaction with 9 steps
1: oxalyl chloride, Me2SO, triethylamine
2: magnesium, water
3: 87 percent / pyridine / CH2Cl2 / 1.) addition over 2 min, -78 deg C, 2.) 0 deg C, 2.5 h
4: 1.) hydrochloric acid, 2.) water
5: 95 percent / pyridine / CH2Cl2
6: 75 percent / phosphorus pentasulfide, triethylamine / CH2Cl2
7: 93 percent / zinc dust, glacial acetic acid / 1.5 h / Ambient temperature
8: 27 percent / aluminum isopropoxide / acetone; benzene
9: 90 percent / p-toluenesulfonic acid monohydrate / benzene / 1 h / Heating; removal of water
With
pyridine; hydrogenchloride; diphosphorus pentasulfide; oxalyl dichloride; water; aluminum isopropoxide; toluene-4-sulfonic acid; magnesium; acetic acid; dimethyl sulfoxide; triethylamine; zinc;
In
dichloromethane; acetone; benzene;
DOI:10.1021/jo01298a022
