t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

Base Information

Chemical Name:t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate
CAS No.:1266116-59-9
Molecular Formula:C₂₇H₄₀N₂O₃
Molecular Weight:440.626
Hs Code.:

Synonyms:t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

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Chemical Property of t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

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Technology Process of t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

There total 6 articles about t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₇H₃₈N₂O₃

: 1266116-59-9
t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

Guidance literature:: C₂₇H₃₈N₂O₃; With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane;

With water; sodium hydrogencarbonate; In 1,2-dichloro-ethane;

Reference yield:

: 1266116-57-7
6-((trans-4-(tert-butyl)cyclohexyl)oxy)quinoline-2-carbaldehyde

: 15231-41-1
tert-butyl 3-aminopropanoate

: 1266116-59-9
t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

Guidance literature:: With sodium tris(acetoxy)borohydride; In dichloromethane;

Reference yield:

: 937-05-3
cis-4-tert-butyl-1-cyclohexanol

: 1266116-59-9
t-butyl 3-(((6-((trans)-4-tert-butylcyclohexyloxy)-quinolin-2-yl)methyl)amino)propionate

Guidance literature:: Multi-step reaction with 3 steps

1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 72 h / 20 °C / Cooling with ice

2: tert.-butylhydroperoxide; selenium(IV) oxide / 1,4-dioxane

3: sodium tris(acetoxy)borohydride / dichloromethane

With tert.-butylhydroperoxide; selenium(IV) oxide; di-isopropyl azodicarboxylate; sodium tris(acetoxy)borohydride; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;