Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)-

Base Information

Chemical Name:Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)-
CAS No.:70521-94-7
Molecular Formula:C₁₂H₁₂N₂O₃
Molecular Weight:232.239
Hs Code.:
NSC Number:324609
DSSTox Substance ID:DTXSID90990729

Synonyms:sesbanine;sesbanine, cis-(+-)-isomer;sesbanine, trans-(+-)-isomer

Suppliers and Price of Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)-

Chemical Property:

Boiling Point:528.3°Cat760mmHg
Flash Point:273.3°C
PSA：79.29000
Density:1.44g/cm³
LogP:0.46300
XLogP3:-0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:371

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CC1O)C3=C(C=NC=C3)C(=O)NC2=O

Technology Process of Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)-

There total 1 articles about Spiro(cyclopentane-1,4'(1'H)-(2,7)naphthyridine)-1',3'(2'H)-dione, 3-hydroxy-, trans-(+)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5444-01-9
3-cyano-4-methylpyridine

: 70521-94-7,72776-95-5,75023-52-8,120019-94-5
+/-10-epi-sesbanine

Guidance literature:: Multi-step reaction with 3 steps

1: 53 percent / sodium hydride / toluene / 9 h / Heating

2: potassium carbonate / ethanol / 24 h / 15 °C

3: sodium hydroxide, 30percent hydrogen peroxide / ethanol / Ambient temperature

With sodium hydroxide; dihydrogen peroxide; sodium hydride; potassium carbonate; In ethanol; toluene;
DOI:10.1016/S0040-4020(01)86137-8

Reference yield:

: 70521-94-7,72776-95-5,75023-52-8,120019-94-5
+/-10-epi-sesbanine

: 74991-81-4
(1R,3S)-1-(3-Cyano-pyridin-4-yl)-3-(toluene-4-sulfonyloxy)-cyclopentanecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / Jones reagent / 4 h / Ambient temperature

2: 67 percent / pyridine / 24 h / Ambient temperature

With pyridine; jones reagent;
DOI:10.1016/S0040-4039(00)71454-7