3-Cyano-4-methylpyridine

Base Information

Chemical Name:3-Cyano-4-methylpyridine
CAS No.:5444-01-9
Molecular Formula:C7H6N2
Molecular Weight:118.138
Hs Code.:29333990
NSC Number:19882
DSSTox Substance ID:DTXSID70281046
Nikkaji Number:J2.402.933F
Wikidata:Q72458609
Mol file:5444-01-9.mol

Synonyms:4-methyl-3-cyanopyridine

Suppliers and Price of 3-Cyano-4-methylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Cyano-4-methylpyridine
500mg
$ 120.00

TCI Chemical
3-Cyano-4-methylpyridine >98.0%(GC)
1g
$ 56.00

TCI Chemical
3-Cyano-4-methylpyridine >98.0%(GC)
5g
$ 196.00

SynQuest Laboratories
4-Methylnicotinonitrile 97%
25 g
$ 119.00

SynQuest Laboratories
4-Methylnicotinonitrile 97%
5 g
$ 31.00

SynQuest Laboratories
4-Methylnicotinonitrile 97%
1 g
$ 16.00

Matrix Scientific
3-Cyano-4-methylpyridine 98%
25g
$ 85.00

Matrix Scientific
3-Cyano-4-methylpyridine 98%
5g
$ 24.00

Matrix Scientific
3-Cyano-4-methylpyridine 98%
100g
$ 245.00

Frontier Specialty Chemicals
3-Cyano-4-methylpyridine 98%
5g
$ 135.00

Total 89 raw suppliers

Chemical Property of 3-Cyano-4-methylpyridine

Chemical Property:

Appearance/Colour:White powder
Vapor Pressure:0.061mmHg at 25°C
Melting Point:41-44 °C
Refractive Index:1.531
Boiling Point:231.723 °C at 760 mmHg
PKA:2.45±0.18(Predicted)
Flash Point:92.223 °C
PSA：36.68000
Density:1.084 g/cm³
LogP:1.26168
Storage Temp.:Keep Cold
Solubility.:soluble in Methanol
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:118.053098200
Heavy Atom Count:9
Complexity:133

Purity/Quality:

99% ^*data from raw suppliers

3-Cyano-4-methylpyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38-36/38-22
Safety Statements: 22-36/37/39-36-26-36/37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=NC=C1)C#N
Uses 3-Cyano-4-methylpyridine, is an intermediate for the synthesis of various pharmaceutical compounds, including inhibitors and anticancer agents. It can be used for the preparation of a series of azaindenoisoquinoline topoisomerase I I inhibitors and potential anticancer agents.

Technology Process of 3-Cyano-4-methylpyridine

There total 19 articles about 3-Cyano-4-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 875-35-4
2,6-dichloro-4-methylnicotinonitrile

: 5444-01-9
3-cyano-4-methylpyridine

Guidance literature:: With hydrogen; sodium acetate; palladium dichloride; In methanol; at 23 ℃; for 14h; under 760.051 Torr;
DOI:10.1021/jm201512x

Reference yield: 85.0%

: 875-35-4
2,6-dichloro-4-methylnicotinonitrile

: palladium dichloride

: 5444-01-9
3-cyano-4-methylpyridine

Guidance literature:: With sodium acetate; In methanol;

Reference yield: 82.0%

: 557-21-1
zinc(II) cyanide

: 3430-22-6
3-Bromo-4-methylpyridin

: 5444-01-9
3-cyano-4-methylpyridine

Guidance literature:: With 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; zinc; In N,N-dimethyl-formamide; at 100 ℃; for 16h; Inert atmosphere;