1-(2'-hydroxyethyl)-1,4-cyclohexadiene

Base Information

• Chemical Name: 1-(2'-hydroxyethyl)-1,4-cyclohexadiene
• CAS No.: 71647-37-5
• Molecular Formula: C₈H₁₂O
• Molecular Weight: 124.183
• Mol file: 71647-37-5.mol

Synonyms:1-(2'-hydroxyethyl)-1,4-cyclohexadiene

Chemical Property of 1-(2'-hydroxyethyl)-1,4-cyclohexadiene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(2'-hydroxyethyl)-1,4-cyclohexadiene

There total 5 articles about 1-(2'-hydroxyethyl)-1,4-cyclohexadiene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-phenylethanol (60-12-8) → 1-(2'-hydroxyethyl)-1,4-cyclohexadiene (71647-37-5)

Guidance literature:

With N,N'-Dimethylurea; tris(pyrrolidino)phosphine oxide; lithium bromide; In tetrahydrofuran; at 20 ℃; Electrochemical reaction;

DOI:10.1126/science.aav5606

Reference yield:

styrene oxide (96-09-3) → 2-phenylethanol (60-12-8) + 1-(2'-hydroxyethyl)-1,4-cyclohexadiene (71647-37-5)

Guidance literature:

With ammonia; lithium; tert-butyl alcohol; In tetrahydrofuran; at 20 ℃; Cooling with ice;

DOI:10.1002/hlca.200890250

Reference yield:

trans-tricyclo[4.2.0.01,3]oct-4-ene → 1-(2'-hydroxyethyl)-1,4-cyclohexadiene (71647-37-5)

Guidance literature:

trans-tricyclo[4.2.0.0^1,3]oct-4-ene; With acetic acid; at 145 ℃; for 8h;

With lithium aluminium tetrahydride; In diethyl ether; for 2h; Further stages.; Heating;

DOI:10.1021/jo000215r

upstream raw materials:

2-phenylethanol

styrene oxide

Downstream raw materials:

2-(2-Cyclohexa-1,4-dienyl-ethoxymethylene)-malonic acid dimethyl ester

1-(2-(4-methoxyphenoxy)ethyl)-1,4-cyclohexadiene

ferrocene carboxylic acid 2-cyclohexa-1,4-dienyl-ethyl ester

C₂₂H₃₀O₃