O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate

Base Information

Chemical Name:O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate
CAS No.:1158348-59-4
Molecular Formula:C₂₄H₁₅ClF₂N₂O₄S
Molecular Weight:500.91
Hs Code.:

Synonyms:O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate

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Chemical Property of O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate

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Technology Process of O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate

There total 1 articles about O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 3891-07-4
N-(2-Hydroxyethyl)phthalimide

: 18355-73-2
2,3-difluorobenzoyl chloride

: 2131-55-7
4-Chlorophenyl isothiocyanate

: 1158348-59-4
O-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethyl] 4-chlorophenyl(2,3-difluorobenzoyl)thiocarbamate

Guidance literature:: N-(2-Hydroxyethyl)phthalimide; 4-Chlorophenyl isothiocyanate; With pyridine; sodium hydride; In mineral oil; at 20 ℃;

2,3-difluorobenzoyl chloride; With N,N,N,N,-tetramethylethylenediamine; In mineral oil; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2008.10.032