Technology Process of C17H21N
There total 1 articles about C17H21N which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-iodo-N,N-diallylaniline;
With
isopropylmagnesium chloride; lithium chloride;
In
tetrahydrofuran;
at -10 ℃;
for 0.5h;
Inert atmosphere;
(E)-5-bromopenta-1,3-diene;
With
copper(l) cyanide; lithium chloride;
In
tetrahydrofuran;
at -10 - 20 ℃;
Inert atmosphere;
DOI:10.1021/ol401901h
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid;
In
dichloromethane;
at 35 ℃;
for 16h;
Inert atmosphere;
DOI:10.1021/ol401901h
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid / dichloromethane / 16 h / 35 °C / Inert atmosphere
2: dichloromethane / 0 - 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); 1,3-dimethylbarbituric acid;
In
dichloromethane;
DOI:10.1021/ol401901h