Technology Process of C19H28O5
There total 11 articles about C19H28O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
toluene;
at -78 ℃;
for 2h;
DOI:10.1039/c3ob42367k
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 1H-imidazole / dichloromethane / 6 h / 0 - 20 °C
2.1: diethylzinc / dichloromethane; hexane / -78 - 20 °C
3.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 0 - 20 °C
5.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h
5.2: 0.42 h / 0 °C
6.1: dichloromethane / 6 h / 20 °C
7.1: diisobutylaluminium hydride / toluene / 2 h / -78 °C
With
1H-imidazole; oxalyl dichloride; tetrabutyl ammonium fluoride; diethylzinc; diisobutylaluminium hydride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane; toluene;
2.1: |Simmons-Smith Cyclopropanation / 5.1: |Swern Oxidation / 5.2: |Swern Oxidation / 6.1: |Wittig Olefination;
DOI:10.1039/c3ob42367k
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: diethylzinc / dichloromethane; hexane / -78 - 20 °C
2.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 12 h / 20 °C
3.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 5 h / 0 - 20 °C
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.42 h
4.2: 0.42 h / 0 °C
5.1: dichloromethane / 6 h / 20 °C
6.1: diisobutylaluminium hydride / toluene / 2 h / -78 °C
With
oxalyl dichloride; tetrabutyl ammonium fluoride; diethylzinc; diisobutylaluminium hydride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; hexane; dichloromethane; toluene;
1.1: |Simmons-Smith Cyclopropanation / 4.1: |Swern Oxidation / 4.2: |Swern Oxidation / 5.1: |Wittig Olefination;
DOI:10.1039/c3ob42367k
