N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide

Base Information

• Chemical Name: N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide
• CAS No.: 119221-50-0
• Molecular Formula: C₄₀H₃₉N₅O₂S
• Molecular Weight: 653.848
• Mol file: 119221-50-0.mol

Synonyms:N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide

Chemical Property of N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide

There total 1 articles about N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

N-[2-(2-Diethylamino-ethyl)-8-hydroxy-2H-6-thia-1,2-diaza-aceanthrylen-5-yl]-2-(trityl-amino)-acetamide; compound with (trityl-amino)-acetic acid (134330-58-8) → N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide (119221-50-0)

Guidance literature:

With triethylamine; In methanol; ethyl acetate; for 3h; Heating;

DOI:10.1002/jhet.5570280261

Reference yield: 78.0%

N-<2-<2-(diethylamino)ethyl>-8-hydroxy-2H<1>benzothiopyrano<4,3,2-cd>indazol-5-yl>-2-<(triphenylmethyl)amino>acetamide (119221-50-0) → 2-<2-(diethylamino)ethyl>-5-<<2-<(triphenylmethyl)amino>ethyl>amino>-2H<1>benzothiopyrano<4,3,2-cd>indazol-8-ol (119221-51-1)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at 80 ℃; for 4.5h;

DOI:10.1002/jhet.5570280261

upstream raw materials:

N-[2-(2-Diethylamino-ethyl)-8-hydroxy-2H-6-thia-1,2-diaza-aceanthrylen-5-yl]-2-(trityl-amino)-acetamide; compound with (trityl-amino)-acetic acid

Downstream raw materials:

2-<2-(diethylamino)ethyl>-5-<<2-<(triphenylmethyl)amino>ethyl>amino>-2H<1>benzothiopyrano<4,3,2-cd>indazol-8-ol