(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

Base Information

Chemical Name:(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate
CAS No.:936703-44-5
Molecular Formula:C₂₅H₃₅NO₇
Molecular Weight:461.555
Hs Code.:

Synonyms:(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

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Chemical Property of (2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

Chemical Property:

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Technology Process of (2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

There total 3 articles about (2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 203057-13-0
(R)-2-(benzyloxy)-2-((S)-3-(tert-butoxycarbonyl)-2,2-dimethyloxazolidin-4-yl)acetic acid

: 936703-44-5
(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / DMAP; EDCl / CH₂Cl₂ / 7 h / 0 - 20 °C

2: aq. Jones reagent / acetone / 12 h / 20 °C

3: 91 percent / K₂CO₃ / dimethylformamide / 12 h / 0 - 20 °C

With dmap; jones reagent; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja068455x

Reference yield:

: 936703-52-5
C₂₅H₃₇NO₆

: 936703-44-5
(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

Guidance literature:: Multi-step reaction with 2 steps

1: aq. Jones reagent / acetone / 12 h / 20 °C

2: 91 percent / K₂CO₃ / dimethylformamide / 12 h / 0 - 20 °C

With jones reagent; potassium carbonate; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja068455x

Reference yield:

: 108-93-0
cyclohexanol

: 936703-44-5
(2R,3R)-1-allyl 4-cyclohexyl 3-(benzyloxy)-2-(tert-butoxycarbonylamino)butane-dioate

Guidance literature:: Multi-step reaction with 3 steps

1: 86 percent / DMAP; EDCl / CH₂Cl₂ / 7 h / 0 - 20 °C

2: aq. Jones reagent / acetone / 12 h / 20 °C

3: 91 percent / K₂CO₃ / dimethylformamide / 12 h / 0 - 20 °C

With dmap; jones reagent; potassium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; acetone;
DOI:10.1021/ja068455x