(S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride

Base Information

• Chemical Name: (S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride
• CAS No.: 77302-68-2
• Molecular Formula: C₃₁H₄₁N₃O₈*ClH
• Molecular Weight: 620.143
• Mol file: 77302-68-2.mol

Synonyms:(S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride

Chemical Property of (S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride

There total 21 articles about (S)-2-[(S)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-2-[(R)-4-Benzyloxycarbonyl-2-((R)-4-benzyloxycarbonyl-2-tert-butoxycarbonylamino-butyrylamino)-butyrylamino]-4-methyl-pentanoic acid methyl ester (77302-90-0) → (S)-2-[(R)-2-((R)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride (77302-68-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

DOI:10.1021/jm00138a013

Reference yield:

(S)-2-[(S)-4-Benzyloxycarbonyl-2-((R)-4-benzyloxycarbonyl-2-tert-butoxycarbonylamino-butyrylamino)-butyrylamino]-4-methyl-pentanoic acid methyl ester (77302-91-1) → (S)-2-[(S)-2-((R)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride (77302-68-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

DOI:10.1021/jm00138a013

Reference yield:

(S)-2-[(R)-4-Benzyloxycarbonyl-2-((S)-4-benzyloxycarbonyl-2-tert-butoxycarbonylamino-butyrylamino)-butyrylamino]-4-methyl-pentanoic acid methyl ester (77302-89-7) → (S)-2-[(R)-2-((S)-2-Amino-4-benzyloxycarbonyl-butyrylamino)-4-benzyloxycarbonyl-butyrylamino]-4-methyl-pentanoic acid methyl ester; hydrochloride (77302-68-2)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; for 1h; Ambient temperature;

DOI:10.1021/jm00138a013

upstream raw materials:

(S)-2-[(S)-4-Benzyloxycarbonyl-2-((R)-4-benzyloxycarbonyl-2-tert-butoxycarbonylamino-butyrylamino)-butyrylamino]-4-methyl-pentanoic acid methyl ester

Boc-Glu(OBzl)-OH

methyl (L)-leucinate hydrochloride

benzyl (S)-4-((tert-butoxycarbonyl)amino)-5-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)amino)-5-oxopentanoate

Downstream raw materials:

(S)-2-{(S)-4-Benzyloxycarbonyl-2-[(R)-4-benzyloxycarbonyl-2-((S)-2-tert-butoxycarbonylamino-4-methyl-pentanoylamino)-butyrylamino]-butyrylamino}-4-methyl-pentanoic acid methyl ester

Boc-Phe-Leu-D-Glu-Glu-Leu-OMe

(S)-2-{(S)-2-[(R)-2-((S)-2-Amino-4-methyl-pentanoylamino)-4-benzyloxycarbonyl-butyrylamino]-4-benzyloxycarbonyl-butyrylamino}-4-methyl-pentanoic acid methyl ester; hydrochloride

(S)-2-((S)-4-Benzyloxycarbonyl-2-{(R)-4-benzyloxycarbonyl-2-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-butyrylamino}-butyrylamino)-4-methyl-pentanoic acid methyl ester